Treatment and Outcome Analysis of 205 Patients with Multidrug-resistant Tuberculosis

Multidrug-resistant tuberculosis, a disease caused by Mycobacterium tuberculosis strains that are resistant at least to rifampin and isoniazid, entails extended treatment, expensive and toxic regimens, and higher rates of treatment failure and death. We retrospectively analyzed the outcomes in 205 p...

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Bibliographic Details
Published in:	American journal of respiratory and critical care medicine Vol. 169; no. 10; pp. 1103 - 1109
Main Authors:	Chan, Edward D, Laurel, Valerie, Strand, Matthew J, Chan, Julanie F, Huynh, Mai-Lan N, Goble, Marian, Iseman, Michael D
Format:	Journal Article
Language:	English
Published:	New York, NY Am Thoracic Soc 15.05.2004 American Lung Association American Thoracic Society
Subjects:	Adolescent Adult Aged Aged, 80 and over Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antitubercular Agents - administration & dosage Biological and medical sciences Child Child, Preschool Clinical outcomes Cohort Studies Drug resistance Drug Resistance, Multiple, Bacterial Drug Therapy, Combination Failure Female Fluoroquinolones - administration & dosage Humans Intensive care medicine Logistic Models Male Medical sciences Microbial Sensitivity Tests Middle Aged Mortality Multidrug resistant organisms Multivariate Analysis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - isolation & purification Patients Prognosis Respiratory failure Retrospective Studies Risk Assessment Severity of Illness Index Sputum - microbiology Success Survival Analysis Thoracic surgery Toxicity Treatment Outcome Tuberculosis Tuberculosis, Multidrug-Resistant - diagnosis Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - mortality Human Treatment resistance Intensive care Prognosis Mycobacterial infection Infection Treatment Tuberculosis Mycobacterium tuberculosis Mycobacteriales Surgery Bacteriosis Mycobacteriaceae Bacteria Actinomycetes drug resistance fluoroquinolones Resuscitation
ISSN:	1073-449X, 1535-4970
Online Access:	Get full text
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