Aerobactin, but not yersiniabactin, salmochelin, or enterobactin, enables the growth/survival of hypervirulent (hypermucoviscous) Klebsiella pneumoniae ex vivo and in vivo

The siderophore aerobactin is the dominant siderophore produced by hypervirulent Klebsiella pneumoniae (hvKP) and was previously shown to be a major virulence factor in systemic infection. However, strains of hvKP commonly produce the additional siderophores yersiniabactin, salmochelin, and enteroba...

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Bibliographic Details
Published in:	Infection and immunity Vol. 83; no. 8; p. 3325
Main Authors:	Russo, Thomas A, Olson, Ruth, MacDonald, Ulrike, Beanan, Janet, Davidson, Bruce A
Format:	Journal Article
Language:	English
Published:	United States 01.08.2015
Subjects:	Animals Enterobactin - analogs & derivatives Enterobactin - metabolism Glucosides - metabolism Humans Hydroxamic Acids - metabolism Klebsiella Infections - microbiology Klebsiella pneumoniae - genetics Klebsiella pneumoniae - growth & development Klebsiella pneumoniae - metabolism Klebsiella pneumoniae - pathogenicity Male Mice Microbial Viability - drug effects Phenols - metabolism Siderophores - metabolism Thiazoles - metabolism Virulence Young Adult
ISSN:	1098-5522, 1098-5522
Online Access:	Get more information
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