Flow cytometry reveals that H5N1 vaccination elicits cross-reactive stem-directed antibodies from multiple Ig heavy-chain lineages

An understanding of the antigen-specific B-cell response to the influenza virus hemagglutinin (HA) is critical to the development of universal influenza vaccines, but it has not been possible to examine these cells directly because HA binds to sialic acid (SA) on most cell types. Here, we use struct...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Journal of virology Ročník 88; číslo 8; s. 4047
Hlavní autori:	Whittle, James R R, Wheatley, Adam K, Wu, Lan, Lingwood, Daniel, Kanekiyo, Masaru, Ma, Steven S, Narpala, Sandeep R, Yassine, Hadi M, Frank, Gregory M, Yewdell, Jonathan W, Ledgerwood, Julie E, Wei, Chih-Jen, McDermott, Adrian B, Graham, Barney S, Koup, Richard A, Nabel, Gary J
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.04.2014
Predmet:	Antibodies, Neutralizing - immunology Antibodies, Viral - immunology B-Lymphocytes - immunology Cross Reactions Flow Cytometry Hemagglutinin Glycoproteins, Influenza Virus - administration & dosage Hemagglutinin Glycoproteins, Influenza Virus - genetics Hemagglutinin Glycoproteins, Influenza Virus - immunology Humans Immunoglobulin G - genetics Immunoglobulin G - immunology Immunoglobulin Heavy Chains - genetics Immunoglobulin Heavy Chains - immunology Influenza A Virus, H5N1 Subtype - immunology Influenza Vaccines - administration & dosage Influenza Vaccines - immunology Influenza, Human - immunology Influenza, Human - prevention & control Influenza, Human - virology Molecular Sequence Data
ISSN:	1098-5514, 1098-5514
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!