Sequential computation of elementary modes and minimal cut sets in genome-scale metabolic networks using alternate integer linear programming

Elementary (flux) modes (EMs) have served as a valuable tool for investigating structural and functional properties of metabolic networks. Identification of the full set of EMs in genome-scale networks remains challenging due to combinatorial explosion of EMs in complex networks. It is often, howeve...

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Bibliographic Details

Published in:	Bioinformatics (Oxford, England) Vol. 33; no. 15; pp. 2345 - 2353
Main Authors:	Song, Hyun-Seob, Goldberg, Noam, Mahajan, Ashutosh, Ramkrishna, Doraiswami
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01.08.2017
Subjects:	Algorithms alternate Interger Linear Programming BASIC BIOLOGICAL SCIENCES Computational Biology - methods Elementary Modes Genome-Scale MATHEMATICS AND COMPUTING Metabolic Networks Metabolic Networks and Pathways Models, Biological Programming, Linear Software
ISSN:	1367-4803, 1367-4811, 1367-4811
Online Access:	Get full text
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