Physical Limit to Concentration Sensing in a Changing Environment

Cells adapt to changing environments by sensing ligand concentrations using specific receptors. The accuracy of sensing is ultimately limited by the finite number of ligand molecules bound by receptors. Previously derived physical limits to sensing accuracy largely have assumed that the concentratio...

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Bibliographic Details

Published in:	Physical review letters Vol. 123; no. 19; p. 198101
Main Authors:	Mora, Thierry, Nemenman, Ilya
Format:	Journal Article
Language:	English
Published:	College Park American Physical Society 05.11.2019
Subjects:	Changing environments Detection Life Sciences Ligands Quantitative Methods Receptors Variations
ISSN:	0031-9007, 1079-7114, 1079-7114
Online Access:	Get full text
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