A wireless optogenetic setup in freely moving mice for evaluation of cortical spreading depolarization in a chronic disease model

Spreading depolarization (SD) is an electrophysiological phenomenon of massive neuronal depolarization that occurs in a multitude of brain injuries. Clinical studies and experimental data have linked the occurrence of SDs with secondary brain damage. However, there is a translational gap because of...

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Bibliographic Details
Published in:	Journal of neuroscience methods Vol. 415; p. 110364
Main Authors:	Köhne, Annika, Helgers, Simeon O.A., Kewitz, Bettina, Haupt, Rieke M., Oppermann, Viktoria, Meinert, Franziska, Sánchez-Porras, Renan, Said, Maryam, Woitzik, Johannes, Dömer, Patrick
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.03.2025
Subjects:	Animals Chronic cerebral hypoperfusion Chronic Disease Cortical Spreading Depression - physiology Disease Models, Animal Internal carotid artery occlusion Male Mice Mice, Inbred C57BL Mice, Transgenic Minimal invasive Neurons - physiology Optogenetic implant Optogenetics - instrumentation Optogenetics - methods Proto-Oncogene Proteins c-fos - metabolism Spreading depression Stroke Wireless optogenetics Wireless Technology - instrumentation Stroke Optogenetic implant Internal carotid artery occlusion Chronic cerebral hypoperfusion Minimal invasive Spreading depression Wireless optogenetics
ISSN:	0165-0270, 1872-678X, 1872-678X
Online Access:	Get full text
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