Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy

Here, we discuss recent evidence that an absence of stromal Cav-1 expression in human breast cancers is a powerful single independent predictor of early disease recurrence, metastasis, and poor clinical outcome. These findings have now been validated in two independent patient populations. Important...

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Bibliographic Details
Published in:	Cell cycle (Georgetown, Tex.) Vol. 8; no. 11; pp. 1654 - 1658
Main Authors:	Witkiewicz, Agnieszka K., Casimiro, Mathew C., Dasgupta, Abhijit, Mercier, Isabelle, Wang, Chenguang, Bonuccelli, Gloria, Jasmin, Jean-François, Frank, Philippe G., Pestell, Richard G., Kleer, Celina G., Sotgia, Federica, Lisanti, Michael P.
Format:	Journal Article
Language:	English
Published:	United States Taylor & Francis 01.06.2009
Subjects:	Angiogenesis Inhibitors - therapeutic use Binding Biology Bioscience Breast Neoplasms - classification Breast Neoplasms - diagnosis Breast Neoplasms - therapy Calcium Cancer Caveolin 1 - metabolism Cell Cycle Female Fibroblasts - metabolism Fibroblasts - physiology Humans Landes Organogenesis Prognosis Proteins Risk Stromal Cells - metabolism Survival Analysis Up-Regulation
ISSN:	1538-4101, 1551-4005, 1551-4005
Online Access:	Get full text
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