Design, synthesis, biological evaluation, and bio-computational modeling of imidazo, thieno, pyrimidopyrimidine, pyrimidodiazepene, and motifs as antimicrobial agents

In the drug chemistry industry, synthesizing a talented exclusive series of aza-polyheterocyclic compounds was crucial. Aminopyrimidine nucleus reacted with two equivalents of benzaldehyde in the presence of KOH as a starting material to bring about imidazopyrimidine derivative, which experienced in...

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Bibliographic Details

Published in:	Heterocyclic Communications Vol. 29; no. 1; pp. 1494 - 501
Main Authors:	El-Ahwany Maged F., Assy Mohamed G., Sherif Mohamed H., Soliman Mohamed R., Titi Abderrahim, Touzani Rachid, El-Gendey Marwa S., Shehab Wesam S., Abdellattif Magda H.
Format:	Journal Article
Language:	English
Published:	Berlin Walter de Gruyter GmbH 01.01.2023 De Gruyter
Subjects:	Acetylacetone Antimicrobial agents Benzaldehyde Carbon disulfide Chemical synthesis Condensates Cycloaddition Fungicides imidazopyrimidine Molecular docking pom studies pyrimidodiazepene pyrimidopyrimidine thienopyrimidine
ISSN:	0793-0283, 2191-0197
Online Access:	Get full text
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