Development and Evaluation of Thermosensitive Hydrogels with Binary Mixture of Scutellariae baicalensis radix Extract and Chitosan for Periodontal Diseases Treatment

Scutellaria baicalensis root displays anti-inflammatory and antibacterial properties due to the presence of flavonoids, particularly baicalin, baicalein, and wogonin. Our work aimed at developing thermosensitive hydrogels containing a binary mixture of S. baicalensis radix lyophilized extract and ch...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 22; no. 21; p. 11319
Main Authors:	Chanaj-Kaczmarek, Justyna, Osmałek, Tomasz, Szymańska, Emilia, Winnicka, Katarzyna, Karpiński, Tomasz M., Dyba, Magdalena, Bekalarska-Dębek, Marta, Cielecka-Piontek, Judyta
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 20.10.2021 MDPI
Subjects:	Animals Antibiotics Bacteria Biopolymers Cellulose Chitosan - administration & dosage Chitosan - pharmacology Chromatography Cytokines Dental plaque Disease Drugs, Chinese Herbal - pharmacology Flavanones - pharmacology Flavonoids Flavonoids - pharmacology Fourier transforms Gum disease Hydrogels Hydrogels - analysis Hydrogels - chemistry Hydrogels - pharmacology Kinases Ligaments Microorganisms Mouth Mucosa - drug effects Mouth Mucosa - metabolism Periodontal Diseases - drug therapy Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Roots Polymers Proteins Scutellaria baicalensis - metabolism Signal transduction Spectrum analysis Swine Viscosity chitosan dissolution studies Scutellaria baicalensis periodontal diseases ex vivo mucoadhesion permeability
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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