Who's in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond

The eukaryotic endomembrane system consists of multiple interconnected organelles. Rab GTPases are organelle-specific markers that give identity to these membranes by recruiting transport and trafficking proteins. During transport processes or along organelle maturation, one Rab is replaced by anoth...

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Bibliographic Details
Published in:	The Journal of cell biology Vol. 220; no. 9
Main Authors:	Borchers, Ann-Christin, Langemeyer, Lars, Ungermann, Christian
Format:	Journal Article
Language:	English
Published:	United States 06.09.2021
Subjects:	Animals Autophagosomes - genetics Autophagosomes - metabolism Biological Transport Cell Membrane - genetics Cell Membrane - metabolism Conserved Sequence Endosomes - genetics Endosomes - metabolism Gene Expression Regulation Guanine Nucleotide Exchange Factors - genetics Guanine Nucleotide Exchange Factors - metabolism Humans Lysosomes - genetics Lysosomes - metabolism Organelle Biogenesis rab GTP-Binding Proteins - genetics rab GTP-Binding Proteins - metabolism rab5 GTP-Binding Proteins - genetics rab5 GTP-Binding Proteins - metabolism rab7 GTP-Binding Proteins Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Signal Transduction Vesicular Transport Proteins - genetics Vesicular Transport Proteins - metabolism
ISSN:	1540-8140, 1540-8140
Online Access:	Get more information
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