Tumour Seeding in the Tract of Percutaneous Renal Tumour Biopsy: A Report on Seven Cases from a UK Tertiary Referral Centre

The role of percutaneous renal tumour biopsy (RTB) in the management of radiological indeterminate renal masses is long established. Patients with small renal masses who have biopsy-proven renal cell carcinoma (RCC) may be offered surgery, ablative therapy, or active surveillance, and RTB can provid...

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Bibliographic Details
Published in:European urology Vol. 75; no. 5; pp. 861 - 867
Main Authors: Macklin, Philip S., Sullivan, Mark E., Tapping, Charles R., Cranston, David W., Webster, Guy M., Roberts, Ian S.D., Verrill, Clare L., Browning, Lisa
Format: Journal Article
Language:English
Published: Switzerland Elsevier B.V 01.05.2019
Subjects:
Adult
Aged
Biopsy
Biopsy, Needle - adverse effects
Biopsy, Needle - methods
Carcinoma
Carcinoma, Renal Cell - diagnosis
Carcinoma, Renal Cell - pathology
Carcinoma, Renal Cell - surgery
Female
Humans
Kidney - pathology
Kidney Neoplasms - diagnosis
Kidney Neoplasms - pathology
Kidney Neoplasms - surgery
Male
Middle Aged
Neoplasm Recurrence, Local - etiology
Neoplasm Recurrence, Local - pathology
Neoplasm Seeding
Renal
Seeding
Tertiary Care Centers
Tumour
United Kingdom
United Kingdom
Carcinoma
Tumour
Renal
Biopsy
Seeding
ISSN:0302-2838, 1873-7560, 1873-7560
Online Access:Get full text
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Summary:The role of percutaneous renal tumour biopsy (RTB) in the management of radiological indeterminate renal masses is long established. Patients with small renal masses who have biopsy-proven renal cell carcinoma (RCC) may be offered surgery, ablative therapy, or active surveillance, and RTB can provide diagnostic tissue from patients with metastatic disease who might benefit from systemic therapy. Current guidelines suggest that tumour seeding along the needle tract is anecdotal, but several cases have been reported recently, although some have been associated with lack of a coaxial sheath. We report on seven patients who underwent surgical resection of RCC in our tertiary referral institution following diagnostic RTB between 2014 and 2017 for whom RTB tract seeding by tumour was identified on histological examination of the resection specimen. One of these patients subsequently developed local tumour recurrence at the site of the previous biopsy.
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ISSN:0302-2838
1873-7560
1873-7560
DOI:10.1016/j.eururo.2018.12.011