Febuxostat‐Induced Agranulocytosis: An Illustrative Case Report and Comprehensive Literature Review

ABSTRACT Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious risk to life. It is essential for healthcare providers to stay alert and informed about this potential adverse reaction.

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Published in:Clinical case reports Vol. 13; no. 9; pp. e70846 - n/a
Main Authors: Liu, Qiuping, Zhong, Bing
Format: Journal Article
Language:English
Published: England John Wiley & Sons, Inc 01.09.2025
Wiley
Subjects:
adverse reaction
Arthritis
Biopsy
Blood
Blood diseases
Bone marrow
Case reports
Drug dosages
febuxostat
granulocytosis
Hospitals
hyperuricemia
Infections
Leukocytes
Literature reviews
Liver
Neutropenia
Neutrophils
Patients
Rheumatism
Uric acid
Vital signs
hyperuricemia
granulocytosis
febuxostat
adverse reaction
ISSN:2050-0904, 2050-0904
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Abstract ABSTRACT Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious risk to life. It is essential for healthcare providers to stay alert and informed about this potential adverse reaction.
AbstractList ABSTRACT Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious risk to life. It is essential for healthcare providers to stay alert and informed about this potential adverse reaction.
Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious risk to life. It is essential for healthcare providers to stay alert and informed about this potential adverse reaction.
ABSTRACT Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious risk to life. It is essential for healthcare providers to stay alert and informed about this potential adverse reaction.
Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious risk to life. It is essential for healthcare providers to stay alert and informed about this potential adverse reaction.Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious risk to life. It is essential for healthcare providers to stay alert and informed about this potential adverse reaction.
Author Liu, Qiuping
Zhong, Bing
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  organization: First Affiliated Hospital of Army Medical University
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  givenname: Bing
  surname: Zhong
  fullname: Zhong, Bing
  email: zhongbing@tmmu.edu.cn
  organization: First Affiliated Hospital of Army Medical University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/40948700$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1002/acr.24180
10.1186/s40360-023-00723-5
10.1111/jcpt.12057
10.1007/s00482-016-0160-3
10.1002/cpt.1377
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10.1007/s40265-015-0360-7
10.1111/j.1600-0609.1996.tb01641.x
10.1097/MD.0000000000005863
10.1016/j.immuni.2021.06.006
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2025 The Author(s). Clinical Case Reports published by John Wiley & Sons Ltd.
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granulocytosis
febuxostat
adverse reaction
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Snippet ABSTRACT Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious...
Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious risk to...
ABSTRACT Neutropenia induced by febuxostat is uncommon, with limited literature available to assess its frequency. This rare complication carries a serious...
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StartPage e70846
SubjectTerms adverse reaction
Arthritis
Biopsy
Blood
Blood diseases
Bone marrow
Case reports
Drug dosages
febuxostat
granulocytosis
Hospitals
hyperuricemia
Infections
Leukocytes
Literature reviews
Liver
Neutropenia
Neutrophils
Patients
Rheumatism
Uric acid
Vital signs
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