hMRP8-ATTAC Mice: A New Model for Conditional and Reversible Neutrophil Ablation

Neutrophils are not only crucial immune cells for the neutralization of pathogens during infections, but they are also key players in tissue repair and cancer. Several methods are available to investigate the in vivo role of neutrophils in these conditions, including the depletion of neutrophils wit...

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Bibliographic Details
Published in:	Cells (Basel, Switzerland) Vol. 11; no. 15; p. 2346
Main Authors:	Duits, Danique E. M., Salvagno, Camilla, Raeven, Elisabeth A. M., Vrijland, Kim, Stip, Marjolein C., Hau, Cheei-Sing, Kaldenbach, Daphne, de Visser, Karin E.
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 30.07.2022 MDPI
Subjects:	Ablation Age Animal models Antibodies Apoptosis Bone marrow Cancer Caspase-8 Cloning CXCR2 protein Dimerization Diphtheria Diphtheria toxin Ethanol Experiments Flow cytometry Fusion protein in vivo neutrophil targeting Injection Laboratories Leukocyte migration Leukocytes (neutrophilic) Macrophage migration inhibitory factor neutrophil depletion Neutrophils novel transgenic mouse model Proteins Rodents Tacrolimus Tacrolimus-binding protein Transgenic mice Tumors United States > US Netherlands
ISSN:	2073-4409, 2073-4409
Online Access:	Get full text
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