Preparation and in vitro evaluation of folate-receptor-targeted SPION-polymer micelle hybrids for MRI contrast enhancement in cancer imaging

Polymer-SPION hybrids were investigated for receptor-mediated localization in tumour tissue. Superparamagnetic iron oxide nanoparticles (SPIONs) prepared by high-temperature decomposition of iron acetylacetonate were monodisperse (9.27 ± 3.37 nm), with high saturation magnetization of 76.8 emu g(-1)...

Full description

Saved in:

Bibliographic Details
Published in:	Nanotechnology Vol. 24; no. 1; p. 015603
Main Authors:	Mahajan, Shveta, Koul, Veena, Choudhary, Veena, Shishodia, Gauri, Bharti, Alok C
Format:	Journal Article
Language:	English
Published:	England 11.01.2013
Subjects:	Cell Death - drug effects Contrast Media Dextrans - chemical synthesis Dextrans - chemistry Dextrans - toxicity Dextrans - ultrastructure Diagnostic Imaging - methods Endocytosis - drug effects Folate Receptor 1 - metabolism HeLa Cells Humans Intracellular Space - drug effects Intracellular Space - metabolism Magnetic Resonance Imaging Magnetite Nanoparticles - chemistry Magnetite Nanoparticles - toxicity Magnetite Nanoparticles - ultrastructure Micelles Microscopy, Confocal Microscopy, Electron, Transmission Neoplasms - diagnosis Neoplasms - pathology Polymerization Polymers - chemical synthesis Polymers - chemistry Pyrenes - chemistry Spectrophotometry, Ultraviolet X-Ray Diffraction
ISSN:	1361-6528, 1361-6528
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!