The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

Background Arachidonic acid (AA) is a long-chain omega-6 polyunsaturated fatty acid (PUFA) synthesized from the precursor dihomo-gamma-linolenic acid (DGLA) that plays a vital role in immunity and inflammation. Variants in the Fatty Acid Desaturase ( FADS ) family of genes on chromosome 11q have bee...

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Bibliographic Details
Published in:	BMC genetics Vol. 12; no. 1; p. 50
Main Authors:	Mathias, Rasika A, Sergeant, Susan, Ruczinski, Ingo, Torgerson, Dara G, Hugenschmidt, Christina E, Kubala, Meghan, Vaidya, Dhananjay, Suktitipat, Bhoom, Ziegler, Julie T, Ivester, Priscilla, Case, Douglas, Yanek, Lisa R, Freedman, Barry I, Rudock, Megan E, Barnes, Kathleen C, Langefeld, Carl D, Becker, Lewis C, Bowden, Donald W, Becker, Diane M, Chilton, Floyd H
Format:	Journal Article
Language:	English
Published:	London BioMed Central 20.05.2011 BMC
Subjects:	8,11,14-Eicosatrienoic Acid - blood African Americans - genetics Animal Genetics and Genomics Arachidonic Acid - blood Biomedical and Life Sciences Chromosomes, Human, Pair 11 European Continental Ancestry Group - genetics Fatty Acids, Omega-6 - metabolism Functional genetics Gene Frequency Genetics and Population Dynamics Humans Life Sciences Microbial Genetics and Genomics Plant Genetics and Genomics Polymorphism, Single Nucleotide Research Article Stearoyl-CoA Desaturase - genetics Arachidonic Acid Level African American Subject Racial Group Linkage Disequilibrium Block Arachidonic Acid
ISSN:	1471-2156, 1471-2156
Online Access:	Get full text
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