Changes in basal and insulin and amino acid response of whole body and skeletal muscle proteins in obese men

Obesity-related insulin resistance of glucose and lipid metabolism may also affect protein kinetics, notably at the muscle level. We hypothesized that muscle protein response to insulin and amino acid is blunted during obesity. Total (Tot) and mitochondrial (Mit) muscle proteins fractional synthesis...

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Bibliographic Details

Published in:	The journal of clinical endocrinology and metabolism Vol. 94; no. 8; p. 3044
Main Authors:	Guillet, Christelle, Delcourt, Ingrid, Rance, Melanie, Giraudet, Christophe, Walrand, Stephane, Bedu, Mario, Duche, Pascale, Boirie, Yves
Format:	Journal Article
Language:	English
Published:	United States 01.08.2009
Subjects:	Adult Amino Acids - metabolism Body Composition Fatty Acids, Nonesterified - metabolism Glucose - metabolism Humans Insulin - blood Insulin - pharmacology Insulin Resistance Leucine - metabolism Male Mitochondrial Proteins - metabolism Muscle Proteins - metabolism Muscle, Skeletal - metabolism Obesity - metabolism
ISSN:	1945-7197, 1945-7197
Online Access:	Get more information
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