Critically evaluated key points on hereditary medullary thyroid carcinoma

Medullary thyroid carcinoma (MTC) accounts for only 3% of all thyroid carcinomas: 75% as sporadic MTC (sMTC) and 25% as hereditary MTC (hMTC) in the context of multiple endocrine neoplasia type 2 (MEN2). Early diagnosis is possible by determining the tumour marker calcitonin (Ctn) when clarifying no...

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Bibliographic Details
Published in:	Frontiers in endocrinology (Lausanne) Vol. 15; p. 1412942
Main Authors:	Zhang, Daqi, Liang, Nan, Sun, Hui, Frattini, Francesco, Sui, Chengqiu, Yang, Mingyu, Wang, Hongbo, Dionigi, Gianlorenzo
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 2024
Subjects:	Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism calcitonin Calcitonin - metabolism Carcinoma, Medullary - congenital Carcinoma, Medullary - diagnosis Carcinoma, Medullary - genetics Carcinoma, Medullary - pathology Carcinoma, Medullary - therapy Carcinoma, Neuroendocrine - diagnosis Carcinoma, Neuroendocrine - genetics Carcinoma, Neuroendocrine - pathology CEA hereditary Humans medullary thyroid carcinoma men Multiple Endocrine Neoplasia Type 2a - diagnosis Multiple Endocrine Neoplasia Type 2a - genetics Multiple Endocrine Neoplasia Type 2a - pathology Multiple Endocrine Neoplasia Type 2a - therapy Mutation Proto-Oncogene Mas Proto-Oncogene Proteins c-ret - genetics thyroid Thyroid Neoplasms - diagnosis Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology Thyroid Neoplasms - therapy Thyroidectomy pathology calcitonin thyroid men diagnosis hereditary medullary thyroid carcinoma CEA
ISSN:	1664-2392, 1664-2392
Online Access:	Get full text
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