ADARp150 counteracts whole genome duplication

Impaired control of the G1/S checkpoint allows initiation of DNA replication under non-permissive conditions. Unscheduled S-phase entry is associated with DNA replication stress, demanding for other checkpoints or cellular pathways to maintain proliferation. Here, we uncovered a requirement for ADAR...

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Bibliographic Details

Published in:	Nucleic acids research Vol. 52; no. 17; pp. 10370 - 10384
Main Authors:	van Gemert, Frank, Drakaki, Alexandra, Lozano, Isabel Morales, de Groot, Daniël, Uiterkamp, Maud Schoot, Proost, Natalie, Lieftink, Cor, van de Ven, Marieke, Beijersbergen, Roderick L, Jacobs, Heinz, te Riele, Hein
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 23.09.2024
Subjects:	Genome Integrity, Repair and
ISSN:	0305-1048, 1362-4962, 1362-4962
Online Access:	Get full text
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