The Safety and Tolerability of Linezolid in Novel Short-Course Regimens Containing Bedaquiline, Pretomanid, and Linezolid to Treat Rifampicin-Resistant Tuberculosis: An Individual Patient Data Meta-analysis

Abstract Background Effectiveness, safety, tolerability, and adherence are critical considerations in shifting to shorter tuberculosis (TB) regimens. Novel 6-month oral regimens that include bedaquiline (B), pretomanid (Pa), and linezolid (L), with or without a fourth drug, have been shown to be as...

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Bibliographic Details

Published in:	Clinical infectious diseases Vol. 78; no. 3; pp. 730 - 741
Main Authors:	Hasan, Tasnim, Medcalf, Ellie, Nyang'wa, Bern-Thomas, Egizi, Erica, Berry, Catherine, Dodd, Matthew, Foraida, Salah, Gegia, Medea, Li, Mengchun, Mirzayev, Fuad, Morgan, Hannah, Motta, Ilaria, Nguyen, Linh, Schumacher, Samuel, Schlub, Tim, Fox, Greg
Format:	Journal Article
Language:	English
Published:	US Oxford University Press 20.03.2024
Subjects:	Antitubercular Agents - adverse effects Diarylquinolines - therapeutic use Humans Linezolid - adverse effects Nitroimidazoles Randomized Controlled Trials as Topic Rifampin - pharmacology Tuberculosis - drug therapy Tuberculosis, Multidrug-Resistant - drug therapy severe adverse events linezolid multidrug-resistant tuberculosis BPaL
ISSN:	1058-4838, 1537-6591, 1537-6591
Online Access:	Get full text
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