Skeletal muscle transcriptomics dissects the pathogenesis of Friedreich’s ataxia

Abstract Objective: In Friedreich’s ataxia (FRDA), the most affected tissues are not accessible to sampling and available transcriptomic findings originate from blood-derived cells and animal models. Herein, we aimed at dissecting for the first time the pathophysiology of FRDA by means of RNA-sequen...

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Bibliographic Details

Published in:	Human molecular genetics Vol. 32; no. 13; pp. 2241 - 2250
Main Authors:	Indelicato, Elisabetta, Kirchmair, Alexander, Amprosi, Matthias, Steixner, Stephan, Nachbauer, Wolfgang, Eigentler, Andreas, Wahl, Nico, Apostolova, Galina, Krogsdam, Anne, Schneider, Rainer, Wanschitz, Julia, Trajanoski, Zlatko, Boesch, Sylvia
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 19.06.2023
Subjects:	Animals Erythropoietin - genetics Friedreich Ataxia - pathology Humans Iron-Binding Proteins - genetics Iron-Binding Proteins - metabolism Leptin - genetics Muscle, Skeletal - metabolism RNA Transcriptome - genetics
ISSN:	0964-6906, 1460-2083, 1460-2083
Online Access:	Get full text
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