A Novel Position-Specific Encoding Algorithm (SeqPose) of Nucleotide Sequences and Its Application for Detecting Enhancers

Enhancers are short genomic regions exerting tissue-specific regulatory roles, usually for remote coding regions. Enhancers are observed in both prokaryotic and eukaryotic genomes, and their detections facilitate a better understanding of the transcriptional regulation mechanism. The accurate detect...

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Vydáno v:	International journal of molecular sciences Ročník 22; číslo 6; s. 3079
Hlavní autoři:	Mu, Xuechen, Wang, Yueying, Duan, Meiyu, Liu, Shuai, Li, Fei, Wang, Xiuli, Zhang, Kai, Huang, Lan, Zhou, Fengfeng
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland MDPI AG 17.03.2021 MDPI
Témata:	Accuracy Algorithms Base Sequence Classification Computational Biology - methods Databases, Genetic Datasets Deep learning Deoxyribonucleic acid DNA Enhancer Elements, Genetic Experiments Feature selection Neural networks Transcription factors text vectorization position-coding attention mechanism two-layer classification model feature selection
ISSN:	1422-0067, 1661-6596, 1422-0067
On-line přístup:	Získat plný text
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