Heparan Sulfate Proteoglycan Signaling in Tumor Microenvironment

In the last few decades, heparan sulfate (HS) proteoglycans (HSPGs) have been an intriguing subject of study for their complex structural characteristics, their finely regulated biosynthetic machinery, and the wide range of functions they perform in living organisms from development to adulthood. Fr...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 21; no. 18; p. 6588
Main Authors:	De Pasquale, Valeria, Pavone, Luigi Michele
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 09.09.2020 MDPI
Subjects:	Acids Biosynthesis Carcinogenesis Collagen Enzymes Genes Glycoproteins Growth factors Heparan sulfate Heparan Sulfate Proteoglycans - chemistry Heparan Sulfate Proteoglycans - metabolism Humans Ligands Lung cancer MAP Kinase Signaling System Metastasis Molecular Structure Molecular Targeted Therapy Mutation Physiology Prostate cancer Proteins Review Signal transduction Skin cancer Thyroid cancer Tumor Microenvironment Tumors remodeling signaling tumor microenvironment heparan sulfate proteoglycans extracellular matrix
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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