Highly Efficient Cardiac Differentiation and Maintenance by Thrombin-Coagulated Fibrin Hydrogels Enriched with Decellularized Porcine Heart Extracellular Matrix

Biochemical and biophysical properties instruct cardiac tissue morphogenesis. Here, we are reporting on a blend of cardiac decellularized extracellular matrix (dECM) from porcine ventricular tissue and fibrinogen that is suitable for investigations employing an in vitro 3D cardiac cell culture model...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 24; no. 3; p. 2842
Main Authors:	Navaee, Fatemeh, Renaud, Philippe, Kleger, Alexander, Braschler, Thomas
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 02.02.2023 MDPI
Subjects:	Animals Cardiomyocytes Cell Differentiation Collagen Collagen - analysis Extracellular matrix Extracellular Matrix - chemistry Fibrin - analysis Heart attacks Hydrogels Hydrogels - analysis Mechanical properties Myocytes, Cardiac Rats Stem cells Swine Thrombin Tissue Engineering - methods Tissue Scaffolds H9c2 cell differentiation beating synchrony neonatal cardiomyocyte culture 3D co-culture dECM-fibrin hydrogel
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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