Comparative Molecular Analysis of Primary Central Nervous System Lymphomas and Matched Vitreoretinal Lymphomas by Vitreous Liquid Biopsy

Primary Central Nervous System Lymphoma (PCNSL) is a lymphoid malignancy of the brain that occurs in ~1500 patients per year in the US. PCNSL can spread to the vitreous and retina, where it is known as vitreoretinal lymphoma (VRL). While confirmatory testing for diagnosis is dependent on invasive br...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 22; no. 18; p. 9992
Main Authors:	Balikov, Daniel A., Hu, Kevin, Liu, Chia-Jen, Betz, Bryan L., Chinnaiyan, Arul M., Devisetty, Laxmi V., Venneti, Sriram, Tomlins, Scott A., Cani, Andi K., Rao, Rajesh C.
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 16.09.2021 MDPI
Subjects:	Biopsy Case Report Cellular biology Central Nervous System Neoplasms - drug therapy Central Nervous System Neoplasms - metabolism Cloning Eye Neoplasms - metabolism Flow cytometry High-Throughput Nucleotide Sequencing Humans Immune system Immunoglobulins Liquid Biopsy Lymphoma Lymphoma, Non-Hodgkin - metabolism Male Methotrexate - therapeutic use Middle Aged Nervous system Patients Remission (Medicine) Retinal Neoplasms - drug therapy Retinal Neoplasms - metabolism Rituximab - therapeutic use Vitreous Body - drug effects Vitreous Body - metabolism United States > US precision diagnostics precision oncology intratumor heterogeneity vitreoretinal lymphoma next generation sequencing primary central nervous system lymphoma
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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