Tumor Microenvironment: A Metabolic Player that Shapes the Immune Response

Immune cells survey and patrol throughout the body and sometimes take residence in niche environments with distinct cellular subtypes and nutrients that may fluctuate from those in which they matured. Rooted in immune cell physiology are metabolic pathways and metabolites that not only deliver subst...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 21; no. 1; p. 157
Main Authors:	Cassim, Shamir, Pouyssegur, Jacques
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 25.12.2019 MDPI
Subjects:	Amino Acids - metabolism Antigens Bioenergetics Biosynthesis Cancer Cell division Enzymes Epigenetics Fatty acids Genotype & phenotype Glucose Glucose - metabolism Humans Immune response Immunity Kinases Lactic Acid - metabolism Lymphocytes Lymphocytes - immunology Lymphocytes - metabolism Medical prognosis Metabolism Mutation Neoplasms - metabolism Neoplasms - pathology Nutrients Review T cell receptors Tumor Microenvironment Tumors microenvironment tumor acidity cancer metabolism immunity lactate nutrients
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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