Metformin raises hydrogen sulfide tissue concentrations in various mouse organs

The epidemic of diabetes mellitus type 2 forces to intensive work on the disease medication. Metformin, the most widely prescribed insulin sensitizer, exerts pleiotropic actions on different tissues by not fully recognized mechanisms. Hydrogen sulfide (H2S) is involved in physiology and pathophysiol...

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Bibliographic Details
Published in:	Pharmacological reports Vol. 65; no. 3; pp. 737 - 742
Main Authors:	Wiliński, Bogdan, Wiliński, Jerzy, Somogyi, Eugeniusz, Piotrowska, Joanna, Opoka, Włodzimierz
Format:	Journal Article
Language:	English
Published:	Cham Elsevier B.V 01.05.2013 Springer International Publishing
Subjects:	Animals biguanide diabetes mellitus Drug Safety and Pharmacovigilance Female hydrogen sulfide Hydrogen Sulfide - metabolism metformin Metformin - pharmacology Mice nitric oxide Pharmacotherapy Pharmacy Short Communication Tissue Distribution - drug effects metformin biguanide nitric oxide diabetes mellitus hydrogen sulfide mice
ISSN:	1734-1140, 2299-5684, 2299-5684
Online Access:	Get full text
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