Modeling Host-Pathogen Interactions in the Context of the Microenvironment: Three-Dimensional Cell Culture Comes of Age

Tissues and organs provide the structural and biochemical landscapes upon which microbial pathogens and commensals function to regulate health and disease. While flat two-dimensional (2-D) monolayers composed of a single cell type have provided important insight into understanding host-pathogen inte...

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Bibliographic Details
Published in:	Infection and immunity Vol. 86; no. 11
Main Authors:	Barrila, Jennifer, Crabbé, Aurélie, Yang, Jiseon, Franco, Karla, Nydam, Seth D, Forsyth, Rebecca J, Davis, Richard R, Gangaraju, Sandhya, Ott, C Mark, Coyne, Carolyn B, Bissell, Mina J, Nickerson, Cheryl A
Format:	Journal Article
Language:	English
Published:	United States 01.11.2018
Subjects:	Cellular Microenvironment History, 20th Century History, 21st Century Host-Pathogen Interactions Humans Intestinal Mucosa - physiology Models, Biological Organ Culture Techniques - history Organ Culture Techniques - methods Organoids Tissue Engineering - history Tissue Engineering - methods RWV 3D host-pathogen interactions mechanotransduction rotating wall vessel gut-on-a-chip 3-D organ-on-a-chip host-microbe interaction organoid
ISSN:	1098-5522, 1098-5522
Online Access:	Get more information
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