Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice

Characterizing germline and somatic ATM variants (gATMm, sATMm) zygosity and their contribution to homologous recombination deficiency (HRD) is important for therapeutic strategy in pancreatic ductal adenocarcinoma (PDAC). Clinico-genomic data for patients with PDAC and other cancers with ATM varian...

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Vydané v:	Clinical cancer research Ročník 28; číslo 21; s. 4782
Hlavní autori:	Park, Wungki, O'Connor, Catherine A, Bandlamudi, Chaitanya, Forman, Daniella, Chou, Joanne F, Umeda, Shigeaki, Reyngold, Marsha, Varghese, Anna M, Keane, Fergus, Balogun, Fiyinfolu, Yu, Kenneth H, Kelsen, David P, Crane, Christopher, Capanu, Marinela, Iacobuzio-Donahue, Christine, O'Reilly, Eileen M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.11.2022
Predmet:	Ataxia Telangiectasia Mutated Proteins - genetics Carcinoma, Pancreatic Ductal - pathology Cohort Studies Genomics Humans Pancreatic Neoplasms Pancreatic Neoplasms - pathology
ISSN:	1557-3265, 1557-3265
On-line prístup:	Zistit podrobnosti o prístupe
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