Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice

Characterizing germline and somatic ATM variants (gATMm, sATMm) zygosity and their contribution to homologous recombination deficiency (HRD) is important for therapeutic strategy in pancreatic ductal adenocarcinoma (PDAC). Clinico-genomic data for patients with PDAC and other cancers with ATM varian...

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Bibliographic Details

Published in:	Clinical cancer research Vol. 28; no. 21; p. 4782
Main Authors:	Park, Wungki, O'Connor, Catherine A, Bandlamudi, Chaitanya, Forman, Daniella, Chou, Joanne F, Umeda, Shigeaki, Reyngold, Marsha, Varghese, Anna M, Keane, Fergus, Balogun, Fiyinfolu, Yu, Kenneth H, Kelsen, David P, Crane, Christopher, Capanu, Marinela, Iacobuzio-Donahue, Christine, O'Reilly, Eileen M
Format:	Journal Article
Language:	English
Published:	United States 01.11.2022
Subjects:	Ataxia Telangiectasia Mutated Proteins - genetics Carcinoma, Pancreatic Ductal - pathology Cohort Studies Genomics Humans Pancreatic Neoplasms Pancreatic Neoplasms - pathology
ISSN:	1557-3265, 1557-3265
Online Access:	Get more information
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