Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice

Characterizing germline and somatic ATM variants (gATMm, sATMm) zygosity and their contribution to homologous recombination deficiency (HRD) is important for therapeutic strategy in pancreatic ductal adenocarcinoma (PDAC). Clinico-genomic data for patients with PDAC and other cancers with ATM varian...

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Veröffentlicht in:	Clinical cancer research Jg. 28; H. 21; S. 4782
Hauptverfasser:	Park, Wungki, O'Connor, Catherine A, Bandlamudi, Chaitanya, Forman, Daniella, Chou, Joanne F, Umeda, Shigeaki, Reyngold, Marsha, Varghese, Anna M, Keane, Fergus, Balogun, Fiyinfolu, Yu, Kenneth H, Kelsen, David P, Crane, Christopher, Capanu, Marinela, Iacobuzio-Donahue, Christine, O'Reilly, Eileen M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.11.2022
Schlagworte:	Ataxia Telangiectasia Mutated Proteins - genetics Carcinoma, Pancreatic Ductal - pathology Cohort Studies Genomics Humans Pancreatic Neoplasms Pancreatic Neoplasms - pathology
ISSN:	1557-3265, 1557-3265
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