Evidence for the Role of Highly Leukotoxic Actinobacillus actinomycetemcomitans in the Pathogenesis of Localized Juvenile and Other Forms of Early‐Onset Periodontitis

Background: Actinobacillus actinomycetemcomitans leukotoxin is thought to be an important virulence factor in the pathogenesis of localized juvenile and other forms of early‐onset periodontitis. Some highly leukotoxic A. actinomycetemcomitans strains produce 10 to 20 times more leukotoxin than other...

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Vydáno v:	Journal of periodontology (1970) Ročník 71; číslo 6; s. 912 - 922
Hlavní autoři:	Haraszthy, Violet I., Hariharan, Govind, Tinoco, Eduardo M.B., Cortelli, Jose R., Lally, Edward T., Davis, Elaine, Zambon, Joseph J.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	737 N. Michigan Avenue, Suite 800, Chicago, IL 60611‐2690, USA American Academy of Periodontology 01.06.2000
Témata:	Actinobacillus actinomycetemcomitans Actinobacillus Infections - genetics Actinobacillus Infections - transmission Adolescent Adult Age Factors Aged Aggregatibacter actinomycetemcomitans - classification Aggregatibacter actinomycetemcomitans - genetics Aggregatibacter actinomycetemcomitans - physiology Aggressive Periodontitis - genetics Aggressive Periodontitis - microbiology Bacterial Toxins - pharmacology Chi-Square Distribution Child Child, Preschool Clone Cells - physiology Cytotoxins - pharmacology Dental Plaque - microbiology Exotoxins - pharmacology Female Humans leukotoxins Male Middle Aged Periodontitis - genetics Periodontitis - microbiology periodontitis, early‐onset/pathogenesis periodontitis, juvenile/pathogenesis periodontitis/pathogenesis Periodontium - microbiology
ISSN:	0022-3492, 1943-3670
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