Attenuation of scopolamine-induced learning deficits by LVV-hemorphin-7 in rats in the passive avoidance and water maze paradigms

Central administration of angiotensin IV (Ang IV) analogues attenuates scopolamine-induced amnesia. Ang IV mediates its effects by binding to a high affinity, binding site, AT 4 receptor, that has recently been identified as insulin regulated aminopeptidase (IRAP). The purpose of this study was to e...

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Bibliographic Details
Published in:	Behavioural brain research Vol. 154; no. 1; pp. 239 - 243
Main Authors:	Albiston, Anthony L, Pederson, Eric S, Burns, Peta, Purcell, Brett, Wright, John W, Harding, Joseph W, Mendelsohn, Frederick A, Weisinger, Richard S, Chai, Siew Yeen
Format:	Journal Article
Language:	English
Published:	Shannon Elsevier B.V 23.09.2004 Elsevier Science
Subjects:	Aminopeptidase Aminopeptidases - metabolism Analysis of Variance Angiotensin Animal Animals AT 4 receptor Avoidance Learning - physiology Behavioral psychophysiology Biological and medical sciences Cognition Cystinyl Aminopeptidase Fundamental and applied biological sciences. Psychology Hemoglobins - metabolism IRAP Learning Learning Disorders - chemically induced Learning Disorders - metabolism Learning Disorders - physiopathology Learning. Memory Male Maze Learning - physiology Neurotransmission and behavior Peptide Fragments - metabolism Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Sprague-Dawley Reaction Time - physiology Receptors, Angiotensin - metabolism Scopolamine Hydrobromide Spatial Behavior - physiology AT 4 receptor IRAP Cognition Aminopeptidase Angiotensin Hyoscine Rat Rodentia Central nervous system Angiotensin receptor Experimental study Encephalon Learning Vertebrata Mammalia Acquisition process Animal Information processing Avoidance
ISSN:	0166-4328, 1872-7549
Online Access:	Get full text
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