IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation

Multiple sclerosis (MS) is an inflammatory neurodegenerative disease of the CNS. Recent advances in whole-genome screening tools have enabled discovery of several MS risk genes, the majority of which have known immune-related functions. However, disease heterogeneity and low tissue accessibility hin...

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Veröffentlicht in:	The Journal of immunology (1950) Jg. 185; H. 11; S. 6883
Hauptverfasser:	Beyeen, Amennai D, Adzemovic, Milena Z, Ockinger, Johan, Stridh, Pernilla, Becanovic, Kristina, Laaksonen, Hannes, Lassmann, Hans, Harris, Robert A, Hillert, Jan, Alfredsson, Lars, Celius, Elisabeth G, Harbo, Hanne F, Kockum, Ingrid, Jagodic, Maja, Olsson, Tomas
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.12.2010
Schlagworte:	Animals Animals, Congenic Crosses, Genetic Encephalomyelitis, Autoimmune, Experimental - genetics Encephalomyelitis, Autoimmune, Experimental - immunology Encephalomyelitis, Autoimmune, Experimental - pathology False Positive Reactions Female Follow-Up Studies Genetic Association Studies - methods Genetic Predisposition to Disease Humans Immunity, Innate - genetics Macrophages, Peritoneal - immunology Macrophages, Peritoneal - metabolism Macrophages, Peritoneal - pathology Male Multiple Sclerosis - genetics Multiple Sclerosis - immunology Multiple Sclerosis - pathology Rats Rats, Inbred Strains Receptors, Interleukin - genetics Receptors, Interleukin - metabolism Receptors, Interleukin - physiology Risk Factors Severity of Illness Index
ISSN:	1550-6606, 1550-6606
Online-Zugang:	Weitere Angaben
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