Biospecific labeling with undecagold: visualization of the biotin-binding site on avidin

The biotin-binding site on avidin has been labeled with biotin conjugated to undecagold, an organometallic cluster compound containing 11 gold atoms in a core angestroms in diameter. Examination of unstained specimens by scanning transmission electron microscopy reveals the labeled sites directly, w...

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Bibliographic Details

Published in:	Science (American Association for the Advancement of Science) Vol. 218; no. 4569; p. 290
Main Authors:	Safer, D, Hainfeld, J, Wall, J S, Reardon, J E
Format:	Journal Article
Language:	English
Published:	United States 15.10.1982
Subjects:	Avidin - metabolism Binding Sites Biotin - metabolism Gold - metabolism Organogold Compounds Organometallic Compounds - metabolism Ovalbumin - analogs & derivatives
ISSN:	0036-8075
Online Access:	Get more information
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