Pharmacological treatment of the biochemical defect in cystic fibrosis airways

The understanding of the biochemical defect in cystic fibrosis (CF) has advanced considerably since discovery of the CF gene in 1989 and characterization of its product. Studies showing that the abnormality in chloride flux could be corrected by transfection of wild-type cystic fibrosis transmembran...

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Vydané v:	The European respiratory journal Ročník 17; číslo 6; s. 1314
Hlavní autori:	Rodgers, H C, Knox, A J
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.06.2001
Predmet:	Animals Chloride Channels - drug effects Chloride Channels - genetics Chloride Channels - physiology Cystic Fibrosis - drug therapy Cystic Fibrosis - genetics Cystic Fibrosis - physiopathology Cystic Fibrosis Transmembrane Conductance Regulator - genetics DNA Mutational Analysis Humans Sodium Channel Blockers - adverse effects Sodium Channel Blockers - therapeutic use Sodium Channels - drug effects Sodium Channels - genetics Sodium Channels - physiology
ISSN:	0903-1936
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