Insulin modulates emotional behavior through a serotonin-dependent mechanism

Type-2 Diabetes (T2D) is characterized by insulin resistance and accompanied by psychiatric comorbidities including major depressive disorders (MDD). Patients with T2D are twice more likely to suffer from MDD and clinical studies have shown that insulin resistance is positively correlated with the s...

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Veröffentlicht in:	Molecular psychiatry Jg. 29; H. 6; S. 1610 - 1619
Hauptverfasser:	Martin, Hugo, Bullich, Sébastien, Martinat, Maud, Chataigner, Mathilde, Di Miceli, Mathieu, Simon, Vincent, Clark, Samantha, Butler, Jasmine, Schell, Mareike, Chopra, Simran, Chaouloff, Francis, Kleinridders, Andre, Cota, Daniela, De Deurwaerdere, Philippe, Pénicaud, Luc, Layé, Sophie, Guiard, Bruno P., Fioramonti, Xavier
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 01.06.2024 Nature Publishing Group
Schlagworte:	38/32 631/378 631/477 64/60 82/16 9/74 Administration, Intranasal Animals Anxiety Anxiolytics Behavioral Sciences Biological Psychology Comorbidity Depressive Disorder, Major Diabetes mellitus Diabetes Mellitus, Type 2 Diet, High-Fat Dorsal Raphe Nucleus Emotional behavior Emotional disorders Emotions High fat diet Insulin Insulin Resistance Life Sciences Male Medicine Medicine & Public Health Mental disorders Mice Mice, Inbred C57BL Mood Mood disorders Neuromodulation Neurons Neurons and Cognition Neurosciences Neurotransmission Pharmacotherapy Psychiatry Receptor, Serotonin, 5-HT1A Serotonergic Neurons Serotonin Serotonin S1 receptors Synaptic Transmission
ISSN:	1359-4184, 1476-5578, 1476-5578
Online-Zugang:	Volltext
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