Role of Nitric Oxide Carried by Hemoglobin in Cardiovascular Physiology: Developments on a Three-Gas Respiratory Cycle

A continuous supply of oxygen is essential for the survival of multicellular organisms. The understanding of how this supply is regulated in the microvasculature has evolved from viewing erythrocytes (red blood cells [RBCs]) as passive carriers of oxygen to recognizing the complex interplay between...

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Bibliographic Details
Published in:	Circulation research Vol. 126; no. 1; p. 129
Main Authors:	Premont, Richard T, Reynolds, James D, Zhang, Rongli, Stamler, Jonathan S
Format:	Journal Article
Language:	English
Published:	United States 03.01.2020
Subjects:	Allosteric Regulation Animals Blood Transfusion Carbon Dioxide - blood Cardiovascular Physiological Phenomena Conserved Sequence Cysteine - metabolism Endothelial Cells - physiology Erythrocytes - metabolism Hemoglobins - genetics Hemoglobins - metabolism Hemoglobins, Abnormal - metabolism Humans Hypoxia - physiopathology Mammals - blood Microcirculation Models, Cardiovascular Nitric Oxide - blood Oxygen - blood Oxyhemoglobins - metabolism Peripheral Arterial Disease - blood Peripheral Arterial Disease - physiopathology S-Nitrosothiols - analysis S-Nitrosothiols - blood Vasodilation - physiology nitric oxide erythrocytes S-nitrosothiols vasodilation heart diseases
ISSN:	1524-4571, 1524-4571
Online Access:	Get more information
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