Biochemical Characteristics of Microbial Enzymes and Their Significance from Industrial Perspectives

Microbes are ubiquitously distributed in nature and are a critical part of the holobiont fitness. They are perceived as the most potential biochemical reservoir of inordinately diverse and multi-functional enzymes. The robust nature of the microbial enzymes with thermostability, pH stability and mul...

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Vydáno v:	Molecular biotechnology Ročník 61; číslo 8; s. 579 - 601
Hlavní autoři:	Thapa, Santosh, Li, Hui, OHair, Joshua, Bhatti, Sarabjit, Chen, Fur-Chi, Nasr, Kamal Al, Johnson, Terrance, Zhou, Suping
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	New York Springer US 01.08.2019 Springer Nature B.V
Témata:	Biochemical characteristics Biochemistry biofuels Biological Techniques Biotechnology Cell Biology Chemical synthesis Chemistry Chemistry and Materials Science Deoxyribonucleic acid Detergents DNA DNA sequencing drugs Enzymes fabrics Feed processing Fitness Food processing Genetic engineering high-throughput nucleotide sequencing Human Genetics Industrial applications manufacturing microbial enzymes Microorganisms Next-generation sequencing Organic chemistry pH stability Polymers Protein Science proteinases Recombinant DNA Refineries Reproductive fitness Review Textiles Therapeutic applications therapeutics Thermal stability Industrial applications Microbial enzymes Recombinant DNA technology Biochemical characteristics
ISSN:	1073-6085, 1559-0305, 1559-0305
On-line přístup:	Získat plný text
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Shrnutí:	Microbes are ubiquitously distributed in nature and are a critical part of the holobiont fitness. They are perceived as the most potential biochemical reservoir of inordinately diverse and multi-functional enzymes. The robust nature of the microbial enzymes with thermostability, pH stability and multi-functionality make them potential candidates for the efficient biotechnological processes under diverse physio-chemical conditions. The need for sustainable solutions to various environmental challenges has further surged the demand for industrial enzymes. Fueled by the recent advent of recombinant DNA technology, genetic engineering, and high-throughput sequencing and omics techniques, numerous microbial enzymes have been developed and further exploited for various industrial and therapeutic applications. Most of the hydrolytic enzymes (protease being the dominant hydrolytic enzyme) have broad range of industrial uses such as food and feed processing, polymer synthesis, production of pharmaceuticals, manufactures of detergents, paper and textiles, and bio-fuel refinery. In this review article, after a short overview of microbial enzymes, an approach has been made to highlight and discuss their potential relevance in biotechnological applications and industrial bio-processes, significant biochemical characteristics of the microbial enzymes, and various tools that are revitalizing the novel enzymes discovery.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Literature Review-3 ObjectType-Review-3 content type line 23
ISSN:	1073-6085 1559-0305 1559-0305
DOI:	10.1007/s12033-019-00187-1