Education, intelligence and Alzheimer’s disease: evidence from a multivariable two-sample Mendelian randomization study

Abstract Objectives To examine whether educational attainment and intelligence have causal effects on risk of Alzheimer’s disease (AD), independently of each other. Design Two-sample univariable and multivariable Mendelian randomization (MR) to estimate the causal effects of education on intelligenc...

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Veröffentlicht in:	International journal of epidemiology Jg. 49; H. 4; S. 1163 - 1172
Hauptverfasser:	Anderson, Emma L, Howe, Laura D, Wade, Kaitlin H, Ben-Shlomo, Yoav, Hill, W David, Deary, Ian J, Sanderson, Eleanor C, Zheng, Jie, Korologou-Linden, Roxanna, Stergiakouli, Evie, Davey Smith, George, Davies, Neil M, Hemani, Gibran
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Oxford University Press 01.08.2020
Schlagworte:	Alzheimer Disease - epidemiology Alzheimer Disease - genetics Educational Status Humans Intelligence Mendelian Randomization Analysis Odds Ratio dementia Mendelian randomization Alzheimer’s disease Education
ISSN:	0300-5771, 1464-3685, 1464-3685
Online-Zugang:	Volltext
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