Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties

•Ocular drug delivery is a field in which regular ADME tools are not useful.•Pharmacokinetics based dosing aid for ocular drug delivery is presented.•User-friendly dosing aid guides early stage design of delivery systems.•Guidance for the delivery route, dosing and formulation design is presented. O...

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Veröffentlicht in:	Drug discovery today Jg. 24; H. 8; S. 1446 - 1457
Hauptverfasser:	Subrizi, Astrid, del Amo, Eva M., Korzhikov-Vlakh, Viktor, Tennikova, Tatiana, Ruponen, Marika, Urtti, Arto
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 01.08.2019
Schlagworte:	Administration, Ophthalmic Biological Availability Drug Delivery Systems - methods Eye - drug effects Humans Ophthalmic Solutions - therapeutic use
ISSN:	1359-6446, 1878-5832, 1878-5832
Online-Zugang:	Volltext
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