Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus

Human CD34(+) hematopoietic progenitor cells obtained from bone marrow (BM), umbilical cord blood (UCB), and mobilized peripheral blood (MPB) were purified and investigated for the expression of the chemokine receptor CXCR4 and its ligand, stromal cell-derived factor-1 (SDF-1). CXCR4 was found prese...

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Bibliographic Details
Published in:	Blood Vol. 94; no. 1; p. 62
Main Authors:	Aiuti, A, Turchetto, L, Cota, M, Cipponi, A, Brambilla, A, Arcelloni, C, Paroni, R, Vicenzi, E, Bordignon, C, Poli, G
Format:	Journal Article
Language:	English
Published:	United States 01.07.1999
Subjects:	Anti-HIV Agents - immunology Anti-HIV Agents - pharmacology Antigens, CD34 Cells, Cultured Chemokine CXCL12 Chemokines, CXC - immunology Chemokines, CXC - pharmacology Hematopoietic Stem Cells - immunology Hematopoietic Stem Cells - virology HIV Infections - immunology HIV-1 - physiology Humans Receptors, CXCR4 - agonists Receptors, CXCR4 - immunology T-Lymphocytes - immunology T-Lymphocytes - virology Virus Replication - immunology
ISSN:	0006-4971
Online Access:	Get more information
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