Enabling the democratization of the genomics revolution with a fully integrated web-based bioinformatics platform

Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Nucleic acids research Ročník 45; číslo 1; s. 67 - 80
Hlavní autori:	Li, Po-E, Lo, Chien-Chi, Anderson, Joseph J., Davenport, Karen W., Bishop-Lilly, Kimberly A., Xu, Yan, Ahmed, Sanaa, Feng, Shihai, Mokashi, Vishwesh P., Chain, Patrick S.G.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Oxford University Press 09.01.2017
Predmet:	Anthrax - microbiology Bacillus anthracis - classification Bacillus anthracis - genetics BASIC BIOLOGICAL SCIENCES Biological Science cloud compatible bioinformatics pipelines and workflows Computational Biology - methods Computer Science Data Resources and Analyses Ebolavirus - classification Ebolavirus - genetics Escherichia coli - classification Escherichia coli - genetics Escherichia coli Infections - microbiology Hemorrhagic Fever, Ebola - virology High-Throughput Nucleotide Sequencing Humans integrated web-based genome analysis Internet isolate and metagenome NGS data analysis and visualization MATHEMATICS AND COMPUTING next generation sequencing genomics and metagenome Phylogeny Plague - microbiology Software Yersinia pestis - classification Yersinia pestis - genetics
ISSN:	0305-1048, 1362-4962, 1362-4962
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Abstract	Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that individually perform fractions of any given analysis, the large number of associated software/hardware dependencies, and the detailed expertise required to perform these analyses. To address these issues, we have developed an intuitive web-based environment with a wide assortment of integrated and cutting-edge bioinformatics tools in pre-configured workflows. These workflows, coupled with the ease of use of the environment, provide even novice next-generation sequencing users with the ability to perform many complex analyses with only a few mouse clicks and, within the context of the same environment, to visualize and further interrogate their results. This bioinformatics platform is an initial attempt at Empowering the Development of Genomics Expertise (EDGE) in a wide range of applications for microbial research.
AbstractList	Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that individually perform fractions of any given analysis, the large number of associated software/hardware dependencies, and the detailed expertise required to perform these analyses. To address these issues, we have developed an intuitive web-based environment with a wide assortment of integrated and cutting-edge bioinformatics tools in pre-configured workflows. These workflows, coupled with the ease of use of the environment, provide even novice next-generation sequencing users with the ability to perform many complex analyses with only a few mouse clicks and, within the context of the same environment, to visualize and further interrogate their results. As a result, this bioinformatics platform is an initial attempt at Empowering the Development of Genomics Expertise (EDGE) in a wide range of applications for microbial research. Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that individually perform fractions of any given analysis, the large number of associated software/hardware dependencies, and the detailed expertise required to perform these analyses. To address these issues, we have developed an intuitive web-based environment with a wide assortment of integrated and cutting-edge bioinformatics tools in pre-configured workflows. These workflows, coupled with the ease of use of the environment, provide even novice next-generation sequencing users with the ability to perform many complex analyses with only a few mouse clicks and, within the context of the same environment, to visualize and further interrogate their results. This bioinformatics platform is an initial attempt at Empowering the Development of Genomics Expertise (EDGE) in a wide range of applications for microbial research.Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that individually perform fractions of any given analysis, the large number of associated software/hardware dependencies, and the detailed expertise required to perform these analyses. To address these issues, we have developed an intuitive web-based environment with a wide assortment of integrated and cutting-edge bioinformatics tools in pre-configured workflows. These workflows, coupled with the ease of use of the environment, provide even novice next-generation sequencing users with the ability to perform many complex analyses with only a few mouse clicks and, within the context of the same environment, to visualize and further interrogate their results. This bioinformatics platform is an initial attempt at Empowering the Development of Genomics Expertise (EDGE) in a wide range of applications for microbial research. Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that individually perform fractions of any given analysis, the large number of associated software/hardware dependencies, and the detailed expertise required to perform these analyses. To address these issues, we have developed an intuitive web-based environment with a wide assortment of integrated and cutting-edge bioinformatics tools in pre-configured workflows. These workflows, coupled with the ease of use of the environment, provide even novice next-generation sequencing users with the ability to perform many complex analyses with only a few mouse clicks and, within the context of the same environment, to visualize and further interrogate their results. This bioinformatics platform is an initial attempt at Empowering the Development of Genomics Expertise (EDGE) in a wide range of applications for microbial research.
Author	Chain, Patrick S.G. Xu, Yan Davenport, Karen W. Lo, Chien-Chi Feng, Shihai Bishop-Lilly, Kimberly A. Li, Po-E Ahmed, Sanaa Mokashi, Vishwesh P. Anderson, Joseph J.
Author_xml	– sequence: 1 givenname: Po-E surname: Li fullname: Li, Po-E – sequence: 2 givenname: Chien-Chi surname: Lo fullname: Lo, Chien-Chi – sequence: 3 givenname: Joseph J. surname: Anderson fullname: Anderson, Joseph J. – sequence: 4 givenname: Karen W. surname: Davenport fullname: Davenport, Karen W. – sequence: 5 givenname: Kimberly A. surname: Bishop-Lilly fullname: Bishop-Lilly, Kimberly A. – sequence: 6 givenname: Yan surname: Xu fullname: Xu, Yan – sequence: 7 givenname: Sanaa surname: Ahmed fullname: Ahmed, Sanaa – sequence: 8 givenname: Shihai surname: Feng fullname: Feng, Shihai – sequence: 9 givenname: Vishwesh P. surname: Mokashi fullname: Mokashi, Vishwesh P. – sequence: 10 givenname: Patrick S.G. surname: Chain fullname: Chain, Patrick S.G.
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/27899609$$D View this record in MEDLINE/PubMed https://www.osti.gov/servlets/purl/1342855$$D View this record in Osti.gov
BookMark	eNptkc9vFCEUx4mpsdvqybuZeDIxY_k1LHMxaZr6I2niRc8EmDezKANbYLqpf710d23UeCDweJ_3fQ--Z-gkxAAIvST4HcE9uwg6XUw_dgTT9RO0IkzQlveCnqAVZrhrCebyFJ3l_B1jwknHn6FTupZ9L3C_QrfXQRvvwtSUDTQDzNEmXdzPumJo4ri_niDE2dncJLiLftmndq5sGt2Mi_f3jQsFploHQ7MD0xqd68m46MIY01y1au3W6_IQPUdPR-0zvDju5-jbh-uvV5_amy8fP19d3rSWY1la0YMhQhpKeiO6UeKBc00Ygc4OdJQgJcWCM9tX3IiRMLwmNaa2wlyMwM7R-4PudjEzDBZCSdqrbXKzTvcqaqf-zgS3UVO8Ux2lnK9ZFXh9EIi5OJWtK2A3NoYAtijCOJVdV6E3xy4p3i6Qi5pdtuC9DhCXrIjkHeX1u0lFX_050OMkv82owNsDYFPMOcH4iBCsHqxW1Wp1tLrS5B-6Tri3rb7G-f_W_AJg17BK
CitedBy_id	crossref_primary_10_1007_s11274_024_04136_2 crossref_primary_10_1016_j_algal_2018_09_012 crossref_primary_10_1371_journal_pntd_0008381 crossref_primary_10_7717_peerj_19832 crossref_primary_10_3390_genes8120350 crossref_primary_10_1016_j_algal_2022_102892 crossref_primary_10_1128_mra_00677_23 crossref_primary_10_3390_md18110558 crossref_primary_10_1186_s40643_020_00314_w crossref_primary_10_3390_genes10080578 crossref_primary_10_1128_mra_01208_24 crossref_primary_10_1373_clinchem_2016_266536 crossref_primary_10_1111_pre_12392 crossref_primary_10_3390_vaccines10060843 crossref_primary_10_1099_ijsem_0_006008 crossref_primary_10_1093_intqhc_mzy236 crossref_primary_10_3389_fgene_2017_00023 crossref_primary_10_1007_s12275_019_9217_1 crossref_primary_10_1128_JVI_00106_19 crossref_primary_10_3389_fmicb_2025_1499516 crossref_primary_10_1016_j_csbj_2022_06_019 crossref_primary_10_1371_journal_pone_0241676 crossref_primary_10_1128_msphere_00345_22 crossref_primary_10_1016_j_biortech_2018_03_050 crossref_primary_10_1016_j_envres_2023_115469 crossref_primary_10_1038_s41598_020_58356_1 crossref_primary_10_1093_gigascience_giz146 crossref_primary_10_1099_mgen_0_001051 crossref_primary_10_3390_antibiotics11020125 crossref_primary_10_1093_nar_gkae1116 crossref_primary_10_3390_microbiolres15030122 crossref_primary_10_1128_mra_01374_18 crossref_primary_10_3390_pathogens10111464 crossref_primary_10_3389_fpubh_2021_648424 crossref_primary_10_1038_s41564_022_01089_w crossref_primary_10_3389_fmicb_2025_1477032 crossref_primary_10_1007_s00248_021_01928_z crossref_primary_10_1371_journal_pntd_0008991 crossref_primary_10_3390_f16040632 crossref_primary_10_1128_mSphere_00759_21 crossref_primary_10_1111_1758_2229_13197 crossref_primary_10_1128_MRA_00853_18 crossref_primary_10_1186_s40168_019_0658_x crossref_primary_10_1038_s42003_021_02693_y crossref_primary_10_1128_MRA_01403_18 crossref_primary_10_1089_hs_2023_0069 crossref_primary_10_1093_infdis_jiz279 crossref_primary_10_3389_fmicb_2019_02537 crossref_primary_10_1093_bib_bbad168 crossref_primary_10_1007_s10452_024_10102_9 crossref_primary_10_1038_s41598_021_94112_9 crossref_primary_10_1038_s41467_020_20199_9 crossref_primary_10_1038_s41598_020_64159_1 crossref_primary_10_1038_s41598_021_98889_7 crossref_primary_10_1016_j_fm_2018_11_005 crossref_primary_10_3390_v16081242 crossref_primary_10_1038_s41467_021_21012_x crossref_primary_10_1099_mgen_0_001180 crossref_primary_10_1128_mra_00949_21 crossref_primary_10_3201_eid2402_171216 crossref_primary_10_3389_fgene_2021_821715 crossref_primary_10_1007_s12223_022_00970_9 crossref_primary_10_3390_v15051077 crossref_primary_10_1128_mra_00106_23 crossref_primary_10_1038_s41598_023_32162_x crossref_primary_10_3390_v10090451 crossref_primary_10_1128_MRA_01368_18 crossref_primary_10_1007_s00294_022_01242_2 crossref_primary_10_1016_j_csbj_2024_09_018 crossref_primary_10_1016_j_onehlt_2025_101109 crossref_primary_10_3390_metabo12121170 crossref_primary_10_1016_j_scitotenv_2020_142755 crossref_primary_10_1093_infdis_jiz286 crossref_primary_10_1186_s12864_019_5543_2 crossref_primary_10_1098_rsos_240108 crossref_primary_10_1111_mmi_14865 crossref_primary_10_1016_j_algal_2020_102041 crossref_primary_10_1089_ast_2021_0089 crossref_primary_10_1093_cid_ciz234 crossref_primary_10_1186_s13765_022_00687_w crossref_primary_10_1038_s41598_024_54195_6 crossref_primary_10_1038_543137a crossref_primary_10_1007_s10103_020_03165_1 crossref_primary_10_3201_eid2607_191707 crossref_primary_10_1128_mra_00131_25 crossref_primary_10_3390_ijms21196979 crossref_primary_10_1371_journal_pone_0302569 crossref_primary_10_3390_v10040188 crossref_primary_10_1007_s10722_023_01652_2 crossref_primary_10_1016_j_watres_2021_117882 crossref_primary_10_1128_MRA_00214_23 crossref_primary_10_3389_fgene_2019_00999 crossref_primary_10_3390_pharmaceutics14081591 crossref_primary_10_1128_spectrum_02564_21 crossref_primary_10_1007_s11274_023_03681_6 crossref_primary_10_1007_s40588_025_00247_y crossref_primary_10_1186_s12879_019_4462_9 crossref_primary_10_3389_fmicb_2024_1401259 crossref_primary_10_3389_fmicb_2021_562157 crossref_primary_10_1016_j_algal_2018_11_023 crossref_primary_10_1007_s10499_024_01723_w crossref_primary_10_1128_mra_00260_24 crossref_primary_10_3389_fmicb_2022_885978 crossref_primary_10_1089_ast_2023_0072 crossref_primary_10_1007_s12551_020_00744_y crossref_primary_10_3390_foods12112140 crossref_primary_10_1016_j_syapm_2025_126643 crossref_primary_10_1128_MRA_00585_19 crossref_primary_10_1099_mgen_0_000276 crossref_primary_10_1128_AEM_01430_18 crossref_primary_10_1007_s10661_024_13025_y crossref_primary_10_3389_fgene_2019_00904 crossref_primary_10_1155_2017_8724304 crossref_primary_10_1371_journal_pone_0184718 crossref_primary_10_3389_fmicb_2022_934708 crossref_primary_10_1007_s42398_019_00058_0 crossref_primary_10_1038_s41598_019_53969_7 crossref_primary_10_1111_jpy_13242 crossref_primary_10_1093_g3journal_jkab074 crossref_primary_10_1128_mra_00107_23 crossref_primary_10_1016_j_virusres_2024_199499 crossref_primary_10_3390_v13081475 crossref_primary_10_1128_mra_00127_25 crossref_primary_10_1016_j_jmoldx_2018_08_008 crossref_primary_10_7717_peerj_15008 crossref_primary_10_1016_j_jviromet_2017_06_005 crossref_primary_10_1128_msystems_00609_19 crossref_primary_10_1111_irv_12717 crossref_primary_10_1186_s42269_019_0208_5 crossref_primary_10_1128_spectrum_01466_24 crossref_primary_10_3201_eid2909_230374 crossref_primary_10_1186_s13099_017_0217_6 crossref_primary_10_1016_j_watres_2022_118415 crossref_primary_10_3390_v14122720 crossref_primary_10_1038_s41598_024_74218_6
Cites_doi	10.1093/nar/gkl732 10.3201/eid1203.051051 10.1126/scitranslmed.3009845 10.1186/s13073-016-0326-8 10.1073/pnas.74.12.5463 10.1093/nar/gkt1226 10.1038/ng0506-500 10.1093/gbe/evu199 10.3201/eid2008.131399 10.1089/cmb.2012.0021 10.1186/s12864-016-2629-y 10.1093/nar/gks596 10.1093/bioinformatics/btu153 10.1073/pnas.0813386106 10.1002/0471142727.mb1910s89 10.1093/nar/gkr771 10.1038/nature11209 10.1006/jmbi.1990.9999 10.1111/j.1469-0691.2005.01309.x 10.1128/genomeA.00151-15 10.1186/s12915-014-0087-z 10.2500/ajra.2013.27.3835 10.1093/nar/gkt1099 10.1111/1574-6968.12106 10.1186/1471-2105-15-126 10.1038/nature03959 10.1186/1471-2105-12-385 10.1186/gb-2004-5-2-r12 10.1128/JCM.41.2.896-899.2003 10.1093/nar/gkt919 10.1128/mBio.00037-15 10.1128/genomeA.00148-15 10.1093/bioinformatics/btu033 10.1371/journal.pone.0040683 10.1186/1754-6834-5-89 10.1186/s12859-014-0366-2 10.1093/bioinformatics/bts174 10.1371/journal.pone.0009490 10.1038/ncomms6498 10.1093/nar/gkq1268 10.1128/JCM.31.6.1511-1514.1993 10.1073/pnas.74.2.560 10.1186/gb-2010-11-1-r1 10.1038/nmeth.1923 10.1371/journal.pone.0012267 10.1186/gb-2014-15-3-r46 10.1093/bib/bbt022 10.1016/j.cancergen.2013.11.005 10.1093/nar/gkv180 10.1038/nmeth.2066 10.1007/978-1-4939-3369-3_13 10.1016/j.bbadis.2014.06.015 10.1101/gr.094607.109 10.1517/14622416.5.4.433
ContentType	Journal Article
Copyright	The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. 2017
Copyright_xml	– notice: The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. – notice: The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. 2017
CorporateAuthor	Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
CorporateAuthor_xml	– name: Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
DBID	AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 OIOZB OTOTI 5PM
DOI	10.1093/nar/gkw1027
DatabaseName	CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic OSTI.GOV - Hybrid OSTI.GOV PubMed Central (Full Participant titles)
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic
DatabaseTitleList	MEDLINE - Academic MEDLINE
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Anatomy & Physiology Chemistry Computer Science
EISSN	1362-4962
EndPage	80
ExternalDocumentID	PMC5224473 1342855 27899609 10_1093_nar_gkw1027
Genre	Journal Article
GroupedDBID	--- -DZ -~X .I3 0R~ 123 18M 1TH 29N 2WC 4.4 482 53G 5VS 5WA 70E 85S A8Z AAFWJ AAHBH AAMVS AAOGV AAPXW AAUQX AAVAP AAYXX ABEJV ABGNP ABPTD ABQLI ABXVV ACGFO ACGFS ACIWK ACNCT ACPRK ACUTJ ADBBV ADHZD AEGXH AENEX AENZO AFFNX AFPKN AFRAH AFYAG AHMBA AIAGR ALMA_UNASSIGNED_HOLDINGS ALUQC AMNDL AOIJS BAWUL BAYMD BCNDV CAG CIDKT CITATION CS3 CZ4 DIK DU5 D~K E3Z EBD EBS EJD EMOBN F5P GROUPED_DOAJ GX1 H13 HH5 HYE HZ~ IH2 KAQDR KQ8 KSI OAWHX OBC OBS OEB OES OJQWA OVT P2P PEELM PQQKQ R44 RD5 RNS ROL ROZ RPM RXO SV3 TN5 TOX TR2 WG7 WOQ X7H XSB YSK ZKX ~91 ~D7 ~KM CGR CUY CVF ECM EIF NPM 7X8 ESTFP AAPPN AFULF BTTYL M49 M~E NU- OIOZB OTOTI ROX 5PM
ID	FETCH-LOGICAL-c408t-69eb168b219b65f80d44a131e5cd2f8e8820643c9c40b6f130716432c65f46fe3
ISICitedReferencesCount	154
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000396575100011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	0305-1048 1362-4962
IngestDate	Tue Sep 30 16:48:26 EDT 2025 Mon Nov 25 02:42:52 EST 2024 Mon Sep 08 16:09:03 EDT 2025 Mon Jul 21 06:04:47 EDT 2025 Sat Nov 29 03:24:41 EST 2025 Tue Nov 18 22:26:32 EST 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	1
Language	English
License	http://creativecommons.org/licenses/by/4.0 The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
LinkModel	OpenURL
MergedId	FETCHMERGED-LOGICAL-c408t-69eb168b219b65f80d44a131e5cd2f8e8820643c9c40b6f130716432c65f46fe3
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 USDOE AC52-06NA25396 LA-UR-15-27035; LA-UR-15-22467 USDOD
ORCID	0000000339493634
OpenAccessLink	http://dx.doi.org/10.1093/nar/gkw1027
PMID	27899609
PQID	1845247891
PQPubID	23479
PageCount	14
ParticipantIDs	pubmedcentral_primary_oai_pubmedcentral_nih_gov_5224473 osti_scitechconnect_1342855 proquest_miscellaneous_1845247891 pubmed_primary_27899609 crossref_primary_10_1093_nar_gkw1027 crossref_citationtrail_10_1093_nar_gkw1027
PublicationCentury	2000
PublicationDate	2017-01-09
PublicationDateYYYYMMDD	2017-01-09
PublicationDate_xml	– month: 01 year: 2017 text: 2017-01-09 day: 09
PublicationDecade	2010
PublicationPlace	England
PublicationPlace_xml	– name: England – name: United States
PublicationTitle	Nucleic acids research
PublicationTitleAlternate	Nucleic Acids Res
PublicationYear	2017
Publisher	Oxford University Press
Publisher_xml	– name: Oxford University Press
References	2017010901005120000_45.1.67.51 2017010901005120000_45.1.67.50 2017010901005120000_45.1.67.13 2017010901005120000_45.1.67.12 2017010901005120000_45.1.67.15 2017010901005120000_45.1.67.14 Rawlings (2017010901005120000_45.1.67.54) 2013; 27 2017010901005120000_45.1.67.53 2017010901005120000_45.1.67.52 2017010901005120000_45.1.67.11 2017010901005120000_45.1.67.55 2017010901005120000_45.1.67.10 2017010901005120000_45.1.67.49 2017010901005120000_45.1.67.40 2017010901005120000_45.1.67.45 Lo (2017010901005120000_45.1.67.23) 2014; 15 2017010901005120000_45.1.67.48 2017010901005120000_45.1.67.47 2017010901005120000_45.1.67.42 2017010901005120000_45.1.67.41 2017010901005120000_45.1.67.44 2017010901005120000_45.1.67.43 2017010901005120000_45.1.67.39 2017010901005120000_45.1.67.38 Hinnebusch (2017010901005120000_45.1.67.46) 1993; 31 2017010901005120000_45.1.67.35 2017010901005120000_45.1.67.34 2017010901005120000_45.1.67.37 2017010901005120000_45.1.67.36 2017010901005120000_45.1.67.31 2017010901005120000_45.1.67.30 2017010901005120000_45.1.67.33 2017010901005120000_45.1.67.32 2017010901005120000_45.1.67.28 2017010901005120000_45.1.67.27 2017010901005120000_45.1.67.29 Buermans (2017010901005120000_45.1.67.1) 2014; 1842 2017010901005120000_45.1.67.2 2017010901005120000_45.1.67.3 2017010901005120000_45.1.67.24 2017010901005120000_45.1.67.4 2017010901005120000_45.1.67.5 2017010901005120000_45.1.67.26 2017010901005120000_45.1.67.6 2017010901005120000_45.1.67.25 2017010901005120000_45.1.67.7 2017010901005120000_45.1.67.20 2017010901005120000_45.1.67.8 2017010901005120000_45.1.67.9 2017010901005120000_45.1.67.22 2017010901005120000_45.1.67.21 2017010901005120000_45.1.67.17 2017010901005120000_45.1.67.16 2017010901005120000_45.1.67.19 2017010901005120000_45.1.67.18
References_xml	– ident: 2017010901005120000_45.1.67.34 doi: 10.1093/nar/gkl732 – ident: 2017010901005120000_45.1.67.47 doi: 10.3201/eid1203.051051 – ident: 2017010901005120000_45.1.67.2 doi: 10.1126/scitranslmed.3009845 – ident: 2017010901005120000_45.1.67.52 doi: 10.1186/s13073-016-0326-8 – ident: 2017010901005120000_45.1.67.11 doi: 10.1073/pnas.74.12.5463 – ident: 2017010901005120000_45.1.67.17 doi: 10.1093/nar/gkt1226 – ident: 2017010901005120000_45.1.67.15 doi: 10.1038/ng0506-500 – ident: 2017010901005120000_45.1.67.4 doi: 10.1093/gbe/evu199 – ident: 2017010901005120000_45.1.67.3 doi: 10.3201/eid2008.131399 – ident: 2017010901005120000_45.1.67.27 doi: 10.1089/cmb.2012.0021 – ident: 2017010901005120000_45.1.67.16 doi: 10.1186/s12864-016-2629-y – ident: 2017010901005120000_45.1.67.35 doi: 10.1093/nar/gks596 – ident: 2017010901005120000_45.1.67.36 doi: 10.1093/bioinformatics/btu153 – ident: 2017010901005120000_45.1.67.39 doi: 10.1073/pnas.0813386106 – ident: 2017010901005120000_45.1.67.13 doi: 10.1002/0471142727.mb1910s89 – ident: 2017010901005120000_45.1.67.44 doi: 10.1093/nar/gkr771 – ident: 2017010901005120000_45.1.67.50 doi: 10.1038/nature11209 – ident: 2017010901005120000_45.1.67.20 doi: 10.1006/jmbi.1990.9999 – ident: 2017010901005120000_45.1.67.53 doi: 10.1111/j.1469-0691.2005.01309.x – ident: 2017010901005120000_45.1.67.40 doi: 10.1128/genomeA.00151-15 – ident: 2017010901005120000_45.1.67.51 doi: 10.1186/s12915-014-0087-z – volume: 27 start-page: 39 year: 2013 ident: 2017010901005120000_45.1.67.54 article-title: Bacterial pathogens in the nasopharynx, nasal cavity, and osteomeatal complex during wellness and viral infection publication-title: Am. J. Rhinol. Allergy doi: 10.2500/ajra.2013.27.3835 – ident: 2017010901005120000_45.1.67.14 doi: 10.1093/nar/gkt1099 – ident: 2017010901005120000_45.1.67.42 doi: 10.1111/1574-6968.12106 – ident: 2017010901005120000_45.1.67.6 doi: 10.1186/1471-2105-15-126 – ident: 2017010901005120000_45.1.67.9 doi: 10.1038/nature03959 – ident: 2017010901005120000_45.1.67.31 doi: 10.1186/1471-2105-12-385 – ident: 2017010901005120000_45.1.67.33 doi: 10.1186/gb-2004-5-2-r12 – ident: 2017010901005120000_45.1.67.49 doi: 10.1128/JCM.41.2.896-899.2003 – ident: 2017010901005120000_45.1.67.18 doi: 10.1093/nar/gkt919 – ident: 2017010901005120000_45.1.67.55 doi: 10.1128/mBio.00037-15 – ident: 2017010901005120000_45.1.67.41 doi: 10.1128/genomeA.00148-15 – ident: 2017010901005120000_45.1.67.38 doi: 10.1093/bioinformatics/btu033 – ident: 2017010901005120000_45.1.67.45 doi: 10.1371/journal.pone.0040683 – ident: 2017010901005120000_45.1.67.5 doi: 10.1186/1754-6834-5-89 – volume: 15 start-page: 366 year: 2014 ident: 2017010901005120000_45.1.67.23 article-title: Rapid evaluation and quality control of next generation sequencing data with FaQCs publication-title: BMC Bioinformatics doi: 10.1186/s12859-014-0366-2 – ident: 2017010901005120000_45.1.67.26 doi: 10.1093/bioinformatics/bts174 – ident: 2017010901005120000_45.1.67.24 doi: 10.1371/journal.pone.0009490 – ident: 2017010901005120000_45.1.67.43 doi: 10.1038/ncomms6498 – ident: 2017010901005120000_45.1.67.37 doi: 10.1093/nar/gkq1268 – volume: 31 start-page: 1511 year: 1993 ident: 2017010901005120000_45.1.67.46 article-title: New method for plague surveillance using polymerase chain reaction to detect Yersinia pestis in fleas publication-title: J. Clin. Microbiol. doi: 10.1128/JCM.31.6.1511-1514.1993 – ident: 2017010901005120000_45.1.67.10 doi: 10.1073/pnas.74.2.560 – ident: 2017010901005120000_45.1.67.22 doi: 10.1186/gb-2010-11-1-r1 – ident: 2017010901005120000_45.1.67.21 doi: 10.1038/nmeth.1923 – ident: 2017010901005120000_45.1.67.29 doi: 10.1371/journal.pone.0012267 – ident: 2017010901005120000_45.1.67.30 doi: 10.1186/gb-2014-15-3-r46 – ident: 2017010901005120000_45.1.67.7 doi: 10.1093/bib/bbt022 – ident: 2017010901005120000_45.1.67.8 doi: 10.1016/j.cancergen.2013.11.005 – ident: 2017010901005120000_45.1.67.25 doi: 10.1093/nar/gkv180 – ident: 2017010901005120000_45.1.67.32 doi: 10.1038/nmeth.2066 – ident: 2017010901005120000_45.1.67.19 doi: 10.1007/978-1-4939-3369-3_13 – volume: 1842 start-page: 1932 year: 2014 ident: 2017010901005120000_45.1.67.1 article-title: Next generation sequencing technology: Advances and applications publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbadis.2014.06.015 – ident: 2017010901005120000_45.1.67.28 doi: 10.1101/gr.094607.109 – ident: 2017010901005120000_45.1.67.12 doi: 10.1517/14622416.5.4.433 – ident: 2017010901005120000_45.1.67.48
SSID	ssj0014154
Score	2.5758805
Snippet	Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw...
SourceID	pubmedcentral osti proquest pubmed crossref
SourceType	Open Access Repository Aggregation Database Index Database Enrichment Source
StartPage	67
SubjectTerms	Anthrax - microbiology Bacillus anthracis - classification Bacillus anthracis - genetics BASIC BIOLOGICAL SCIENCES Biological Science cloud compatible bioinformatics pipelines and workflows Computational Biology - methods Computer Science Data Resources and Analyses Ebolavirus - classification Ebolavirus - genetics Escherichia coli - classification Escherichia coli - genetics Escherichia coli Infections - microbiology Hemorrhagic Fever, Ebola - virology High-Throughput Nucleotide Sequencing Humans integrated web-based genome analysis Internet isolate and metagenome NGS data analysis and visualization MATHEMATICS AND COMPUTING next generation sequencing genomics and metagenome Phylogeny Plague - microbiology Software Yersinia pestis - classification Yersinia pestis - genetics
Title	Enabling the democratization of the genomics revolution with a fully integrated web-based bioinformatics platform
URI	https://www.ncbi.nlm.nih.gov/pubmed/27899609 https://www.proquest.com/docview/1845247891 https://www.osti.gov/servlets/purl/1342855 https://pubmed.ncbi.nlm.nih.gov/PMC5224473
Volume	45
WOSCitedRecordID	wos000396575100011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1362-4962 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0014154 issn: 0305-1048 databaseCode: DOA dateStart: 20050101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVASL databaseName: Oxford Journals Open Access Collection customDbUrl: eissn: 1362-4962 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0014154 issn: 0305-1048 databaseCode: TOX dateStart: 19960101 isFulltext: true titleUrlDefault: https://academic.oup.com/journals/ providerName: Oxford University Press
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3fb9owELYom7S9TFu7H7Qb8qSqD6uiEuLEzmPVgfaAaB_oxFsUHGdFg4TSlLb7N_YP7852Euh46B72EoGx4ij3cb47331HyGEIe6z0U8-RPGAOc6Vw4iTAimXJFPekUDp08X3Ah0MxHocXjcbvshZmNeNZJu7vw8V_FTWMgbCxdPYfxF3dFAbgMwgdriB2uD5J8D2shiqLoBI1zyUK-VdlGuIwMrPOkZ95qVb2YWyV2zHG4x9qFonkGPSsg3sdWKrT3PKsam7nxSwu8Nu6fTtEemSkgJXTBO--FivDrB-dOnCRO1X5w8BEaq9AwThwrYMSifYE6jOK-vjqawz6Gb2GqpbNJAmWsQuX69hFuKZudc1WaPWx2jJmdbShnNzAolG4ppfHX_uA4cjKMEe9_-PnHVhRvN7wykP-4XnUvxwMolFvPDpaXDvYigyP7G1flh3yrMv9ELX96HxcHU2BxWM6JdvHtEWfsOIJrHdiV9swc5o5qOttLszjTNw102b0mryyPgk9NVh6Qxoq2yV7p1lc5PMHekR1lrA-ftklL87KDoF75LqEGgVM0UdQo3mqh0uo0RpqFKFGY6qhRmuo0QpqdBNqtITaW3LZ743Ovjm2hYcjWUcUThCCLRCICeyLk8BPRSdhLHY9V_ky6aZCCWwfwDwZwvRJkIJBhf6715UwmQWp8t6RZpZn6gOhIphwyZlI3ViwNPbiVHZSNWFMBWkMa7TIl_KNR9Ly22OblVlk8iy8CMQTWfG0yGE1eWFoXbZPO0DRRWCNIqWyxNwzWUSuB06777fI51KiEbx5PGmLM5Xf3kSuYH6XcRG6LfLeSLhaBkvPkeaxRfiG7KsJSPi--Us2vdLE7-ArMca9_Sese0Be1n-4j6RZLG_VJ_JcrorpzbJNdvhYtHX8qa3R_QcrJ9WY
linkProvider	Oxford University Press
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Enabling+the+democratization+of+the+genomics+revolution+with+a+fully+integrated+web-based+bioinformatics+platform&rft.jtitle=Nucleic+acids+research&rft.au=Li%2C+Po-E&rft.au=Lo%2C+Chien-Chi&rft.au=Anderson%2C+Joseph+J&rft.au=Davenport%2C+Karen+W&rft.date=2017-01-09&rft.issn=1362-4962&rft.eissn=1362-4962&rft.volume=45&rft.issue=1&rft.spage=67&rft_id=info:doi/10.1093%2Fnar%2Fgkw1027&rft.externalDBID=NO_FULL_TEXT
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0305-1048&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0305-1048&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0305-1048&client=summon