Endothelin-1 is elevated in monocrotaline pulmonary hypertension

These studies document striking pulmonary vasoconstrictor response to nitric oxide synthase (NOS) inhibition in monocrotaline (MCT) pulmonary hypertension in rats. This constriction is caused by elevated endothelin (ET)-1 production acting on ET receptors. Isolated, red blood cell plus buffer-perfus...

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Bibliographic Details

Published in:	American journal of physiology. Lung cellular and molecular physiology Vol. 276; no. 2; pp. L304 - L310
Main Authors:	Frasch, H Frederick, Marshall, Carol, Marshall, Bryan E
Format:	Journal Article
Language:	English
Published:	United States 01.02.1999
Subjects:	endothelial function nitric oxide pulmonary vascular resistance pulmonary circulation
ISSN:	0002-9513, 1522-1504
Online Access:	Get more information
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