miR-204-5p inhibits proliferation and invasion and enhances chemotherapeutic sensitivity of colorectal cancer cells by downregulating RAB22A

miR-204-5p was found to be downregulated in colorectal cancer tissues in our preliminary microarray analyses. However, the function of miR-204-5p in colorectal cancer remains unknown. We therefore investigated the role, mechanism, and clinical significance of miR-204-5p in colorectal cancer developm...

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Vydáno v:	Clinical cancer research Ročník 20; číslo 23; s. 6187
Hlavní autoři:	Yin, Yuan, Zhang, Binbin, Wang, Weili, Fei, Bojian, Quan, Chao, Zhang, Jiwei, Song, Mingxu, Bian, Zehua, Wang, Qifeng, Ni, Shujuan, Hu, Yaling, Mao, Yong, Zhou, Leyuan, Wang, Yugang, Yu, Jian, Du, Xiang, Hua, Dong, Huang, Zhaohui
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.12.2014
Témata:	Animals Base Sequence Binding Sites Cell Line, Tumor Cell Movement - genetics Cell Proliferation Cell Transformation, Neoplastic - genetics Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Disease Models, Animal DNA Methylation Down-Regulation Drug Resistance, Neoplasm - genetics Gene Expression Regulation, Neoplastic Humans Male Mice MicroRNAs - chemistry MicroRNAs - genetics Prognosis Promoter Regions, Genetic rab GTP-Binding Proteins - chemistry rab GTP-Binding Proteins - genetics RNA Interference Tumor Burden Xenograft Model Antitumor Assays
ISSN:	1078-0432, 1557-3265, 1557-3265
On-line přístup:	Zjistit podrobnosti o přístupu
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