SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread

Background: Due to rapid spread, the Omicron variant has become the dominant SARS-CoV-2 variant responsible for infections worldwide. We present the first detection of the Omicron variant in Croatia which resulted in rapid cross-border spreading. Methods: Whole-genome sequencing was performed using...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Pathogens (Basel) Ročník 11; číslo 5; s. 511
Hlavní autoři:	Ferenčak, Ivana, Obrovac, Mihaela, Žmak, Ljiljana, Kuzle, Josipa, Petrović, Goranka, Vilibić-Čavlek, Tatjana, Jurić, Dragan, Jurić, Anita, Hruškar, Željka, Capak, Krunoslav, Stevanović, Vladimir, Milanović, Maja, Govedarica, Marija, Vujošević, Danijela, Tabain, Irena
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland MDPI AG 26.04.2022 MDPI
Témata:	Communication Contact tracing Coronaviruses COVID-19 COVID-19 vaccines Croatia Depletion Disease transmission Epidemics Epidemiology Gene sequencing Influenza Laboratories Medical research mRNA Mutation Omicron variant Pandemics Patients Phylogenetics Phylogeny SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 surveillance Viral diseases Whole genome sequencing Workshops South Africa Montenegro Croatia Omicron variant SARS-CoV-2 surveillance whole-genome sequencing Croatia
ISSN:	2076-0817, 2076-0817
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Abstract	Background: Due to rapid spread, the Omicron variant has become the dominant SARS-CoV-2 variant responsible for infections worldwide. We present the first detection of the Omicron variant in Croatia which resulted in rapid cross-border spreading. Methods: Whole-genome sequencing was performed using the Illumina MiniSeq sequencing system. SARS-CoV-2 lineages were identified using the PANGOLIN and GISAID databases. Results: The first case of the Omicron variant (BA.1.17) emerged in Croatia after a workshop held in Zagreb in November 2021. The patient reported a history of previous COVID-19 and received two doses of an mRNA vaccine. Three additional cases were detected among Croatian participants of the workshop. At the beginning of December, SARS-CoV-2 infection was confirmed in one participant from Montenegro and her husband. Phylogenetic analysis showed that the detected Omicron variants were closely related to the first Croatian case, confirming the connection with the workshop outbreak and rapid cross-border spreading. Subsequent analyses of SARS-CoV-2 positive samples in Croatia showed the rapid introduction of the Omicron variant and depletion of the Delta variant resulting in the fifth pandemic wave. Conclusions: Genomic monitoring and early detection of novel SARS-CoV-2 variants are essential to implement timely epidemiological interventions and reduce further transmission in the population.
AbstractList	Due to rapid spread, the Omicron variant has become the dominant SARS-CoV-2 variant responsible for infections worldwide. We present the first detection of the Omicron variant in Croatia which resulted in rapid cross-border spreading. Whole-genome sequencing was performed using the Illumina MiniSeq sequencing system. SARS-CoV-2 lineages were identified using the PANGOLIN and GISAID databases. The first case of the Omicron variant (BA.1.17) emerged in Croatia after a workshop held in Zagreb in November 2021. The patient reported a history of previous COVID-19 and received two doses of an mRNA vaccine. Three additional cases were detected among Croatian participants of the workshop. At the beginning of December, SARS-CoV-2 infection was confirmed in one participant from Montenegro and her husband. Phylogenetic analysis showed that the detected Omicron variants were closely related to the first Croatian case, confirming the connection with the workshop outbreak and rapid cross-border spreading. Subsequent analyses of SARS-CoV-2 positive samples in Croatia showed the rapid introduction of the Omicron variant and depletion of the Delta variant resulting in the fifth pandemic wave. Genomic monitoring and early detection of novel SARS-CoV-2 variants are essential to implement timely epidemiological interventions and reduce further transmission in the population. Background: Due to rapid spread, the Omicron variant has become the dominant SARS-CoV-2 variant responsible for infections worldwide. We present the first detection of the Omicron variant in Croatia which resulted in rapid cross-border spreading. Methods: Whole-genome sequencing was performed using the Illumina MiniSeq sequencing system. SARS-CoV-2 lineages were identified using the PANGOLIN and GISAID databases. Results: The first case of the Omicron variant (BA.1.17) emerged in Croatia after a workshop held in Zagreb in November 2021. The patient reported a history of previous COVID-19 and received two doses of an mRNA vaccine. Three additional cases were detected among Croatian participants of the workshop. At the beginning of December, SARS-CoV-2 infection was confirmed in one participant from Montenegro and her husband. Phylogenetic analysis showed that the detected Omicron variants were closely related to the first Croatian case, confirming the connection with the workshop outbreak and rapid cross-border spreading. Subsequent analyses of SARS-CoV-2 positive samples in Croatia showed the rapid introduction of the Omicron variant and depletion of the Delta variant resulting in the fifth pandemic wave. Conclusions: Genomic monitoring and early detection of novel SARS-CoV-2 variants are essential to implement timely epidemiological interventions and reduce further transmission in the population. Due to rapid spread, the Omicron variant has become the dominant SARS-CoV-2 variant responsible for infections worldwide. We present the first detection of the Omicron variant in Croatia which resulted in rapid cross-border spreading.BACKGROUNDDue to rapid spread, the Omicron variant has become the dominant SARS-CoV-2 variant responsible for infections worldwide. We present the first detection of the Omicron variant in Croatia which resulted in rapid cross-border spreading.Whole-genome sequencing was performed using the Illumina MiniSeq sequencing system. SARS-CoV-2 lineages were identified using the PANGOLIN and GISAID databases.METHODSWhole-genome sequencing was performed using the Illumina MiniSeq sequencing system. SARS-CoV-2 lineages were identified using the PANGOLIN and GISAID databases.The first case of the Omicron variant (BA.1.17) emerged in Croatia after a workshop held in Zagreb in November 2021. The patient reported a history of previous COVID-19 and received two doses of an mRNA vaccine. Three additional cases were detected among Croatian participants of the workshop. At the beginning of December, SARS-CoV-2 infection was confirmed in one participant from Montenegro and her husband. Phylogenetic analysis showed that the detected Omicron variants were closely related to the first Croatian case, confirming the connection with the workshop outbreak and rapid cross-border spreading. Subsequent analyses of SARS-CoV-2 positive samples in Croatia showed the rapid introduction of the Omicron variant and depletion of the Delta variant resulting in the fifth pandemic wave.RESULTSThe first case of the Omicron variant (BA.1.17) emerged in Croatia after a workshop held in Zagreb in November 2021. The patient reported a history of previous COVID-19 and received two doses of an mRNA vaccine. Three additional cases were detected among Croatian participants of the workshop. At the beginning of December, SARS-CoV-2 infection was confirmed in one participant from Montenegro and her husband. Phylogenetic analysis showed that the detected Omicron variants were closely related to the first Croatian case, confirming the connection with the workshop outbreak and rapid cross-border spreading. Subsequent analyses of SARS-CoV-2 positive samples in Croatia showed the rapid introduction of the Omicron variant and depletion of the Delta variant resulting in the fifth pandemic wave.Genomic monitoring and early detection of novel SARS-CoV-2 variants are essential to implement timely epidemiological interventions and reduce further transmission in the population.CONCLUSIONSGenomic monitoring and early detection of novel SARS-CoV-2 variants are essential to implement timely epidemiological interventions and reduce further transmission in the population.
Author	Capak, Krunoslav Stevanović, Vladimir Vujošević, Danijela Tabain, Irena Govedarica, Marija Petrović, Goranka Žmak, Ljiljana Obrovac, Mihaela Ferenčak, Ivana Hruškar, Željka Jurić, Dragan Milanović, Maja Kuzle, Josipa Vilibić-Čavlek, Tatjana Jurić, Anita
AuthorAffiliation	2 Department of Microbiology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia 6 Department of Epidemiology, Institute of Public Health, 81110 Podgorica, Montenegro; maja.milanovic@ijzcg.me (M.M.); marija.govedarica@ijzcg.me (M.G.); danijela.vujosevic@ijzcg.me (D.V.) 5 Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia; vladostevanovic@gmail.com 1 Department of Microbiology, Croatian Institute of Public Health, 10000 Zagreb, Croatia; ivana.ferencak@hzjz.hr (I.F.); mihaela.obrovac@hzjz.hr (M.O.); ljiljana.zmak@hzjz.hr (L.Ž.); josipa.kuzle@hzjz.hr (J.K.); dragan.juric@hzjz.hr (D.J.); misicanita1@gmail.com (A.J.); zeljka.hruskar@hzjz.hr (Ž.H.); irena.tabain@hzjz.hr (I.T.) 3 Department of Epidemiology, Croatian Institute of Public Health, 10000 Zagreb, Croatia; goranka.petrovic@hzjz.hr 4 Environmental Health Department, Croatian Institute of Public Health, 10000 Zagreb, Croatia; kcapak@hzjz.h
AuthorAffiliation_xml	– name: 1 Department of Microbiology, Croatian Institute of Public Health, 10000 Zagreb, Croatia; ivana.ferencak@hzjz.hr (I.F.); mihaela.obrovac@hzjz.hr (M.O.); ljiljana.zmak@hzjz.hr (L.Ž.); josipa.kuzle@hzjz.hr (J.K.); dragan.juric@hzjz.hr (D.J.); misicanita1@gmail.com (A.J.); zeljka.hruskar@hzjz.hr (Ž.H.); irena.tabain@hzjz.hr (I.T.) – name: 3 Department of Epidemiology, Croatian Institute of Public Health, 10000 Zagreb, Croatia; goranka.petrovic@hzjz.hr – name: 5 Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, 10000 Zagreb, Croatia; vladostevanovic@gmail.com – name: 6 Department of Epidemiology, Institute of Public Health, 81110 Podgorica, Montenegro; maja.milanovic@ijzcg.me (M.M.); marija.govedarica@ijzcg.me (M.G.); danijela.vujosevic@ijzcg.me (D.V.) – name: 4 Environmental Health Department, Croatian Institute of Public Health, 10000 Zagreb, Croatia; kcapak@hzjz.hr – name: 2 Department of Microbiology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia
Author_xml	– sequence: 1 givenname: Ivana orcidid: 0000-0002-9285-9052 surname: Ferenčak fullname: Ferenčak, Ivana – sequence: 2 givenname: Mihaela surname: Obrovac fullname: Obrovac, Mihaela – sequence: 3 givenname: Ljiljana surname: Žmak fullname: Žmak, Ljiljana – sequence: 4 givenname: Josipa orcidid: 0000-0003-0434-7514 surname: Kuzle fullname: Kuzle, Josipa – sequence: 5 givenname: Goranka orcidid: 0000-0001-8304-5519 surname: Petrović fullname: Petrović, Goranka – sequence: 6 givenname: Tatjana orcidid: 0000-0002-1877-5547 surname: Vilibić-Čavlek fullname: Vilibić-Čavlek, Tatjana – sequence: 7 givenname: Dragan surname: Jurić fullname: Jurić, Dragan – sequence: 8 givenname: Anita surname: Jurić fullname: Jurić, Anita – sequence: 9 givenname: Željka orcidid: 0000-0002-9078-1773 surname: Hruškar fullname: Hruškar, Željka – sequence: 10 givenname: Krunoslav surname: Capak fullname: Capak, Krunoslav – sequence: 11 givenname: Vladimir surname: Stevanović fullname: Stevanović, Vladimir – sequence: 12 givenname: Maja surname: Milanović fullname: Milanović, Maja – sequence: 13 givenname: Marija surname: Govedarica fullname: Govedarica, Marija – sequence: 14 givenname: Danijela surname: Vujošević fullname: Vujošević, Danijela – sequence: 15 givenname: Irena orcidid: 0000-0002-2518-522X surname: Tabain fullname: Tabain, Irena
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/35631032$$D View this record in MEDLINE/PubMed
BookMark	eNp9ks9u1DAQxiNUREvpA3BBkbhwCfhf4uSCVAKFSpUqdaFXa2JPdr3K2ovtReLGQ_CEPAkOW6q2SPhij_2bz58987Q4cN5hUTyn5DXnHXmzhbTyS3SRUlKTmtJHxREjsqlIS-XBnfVhcRLjmuTRkjl-UhzyuuGUcHZUwOL0alH1_rpi5eXG6uBdeQ3BgkuldWUfPCQLv378vIKtNeV7TKiTzZAfy7TC8syGmMoeIpbgzMzHWL3zwWAoF9uAYJ4Vj0eYIp7czMfFl7MPn_tP1cXlx_P-9KLSIruqRkM6gnIUwAZDO1p3grcDa1sKDZCO10jJMNK6bZmhgjesMYZ3ptM1lzUfBT8uzve6xsNabYPdQPiuPFj1Z8OHpYKQrJ5QNaIhQBtOCHIhRL6h1i3KgSFDMUiStd7utba7YYNGo0sBpnui90-cXaml_6Y6KmpG2izw6kYg-K87jEltbNQ4TeDQ76JijaRMdkzIjL58gK79Lrj8VTNFssG2Y5l6cdfRrZW_lcwA3QN6LkHA8RahRM0No_5pmJwjH-Rom2Aub36Unf6T-RvL8MVB
CitedBy_id	crossref_primary_10_1016_j_healthpol_2024_105056 crossref_primary_10_1080_07391102_2023_2222832 crossref_primary_10_3390_antib12040061 crossref_primary_10_3390_ijerph20031950
Cites_doi	10.1101/2022.01.28.22270044 10.1002/gch2.1018 10.1093/nar/gkab301 10.17504/protocols.io.bbmuik6w 10.3390/v13122354 10.1101/2022.01.25.22269794 10.1056/NEJMc2200133 10.1002/mco2.110 10.1016/j.jviromet.2021.114248 10.1093/ve/veab064 10.2807/1560-7917.ES.2017.22.13.30494 10.1093/bib/bbx108 10.1093/infdis/jiab082 10.1038/s41564-020-0770-5 10.1001/jama.2021.5607
ContentType	Journal Article
Copyright	2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2022 by the authors. 2022
Copyright_xml	– notice: 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2022 by the authors. 2022
DBID	AAYXX CITATION NPM 7T7 8FD 8FE 8FH ABUWG AFKRA AZQEC BBNVY BENPR BHPHI C1K CCPQU COVID DWQXO FR3 GNUQQ HCIFZ LK8 M7P P64 PHGZM PHGZT PIMPY PKEHL PQEST PQGLB PQQKQ PQUKI PRINS 7X8 5PM DOA
DOI	10.3390/pathogens11050511
DatabaseName	CrossRef PubMed Industrial and Applied Microbiology Abstracts (Microbiology A) Technology Research Database ProQuest SciTech Collection ProQuest Natural Science Collection ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection AUTh Library subscriptions: ProQuest Central Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College Coronavirus Research Database ProQuest Central Korea Engineering Research Database ProQuest Central Student SciTech Premium Collection ProQuest Biological Science Collection Biological Science Database Biotechnology and BioEngineering Abstracts ProQuest Central Premium ProQuest One Academic Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) Open Access: DOAJ - Directory of Open Access Journals
DatabaseTitle	CrossRef PubMed Publicly Available Content Database ProQuest Central Student Technology Research Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Natural Science Collection ProQuest Central China Environmental Sciences and Pollution Management ProQuest Central ProQuest One Applied & Life Sciences Natural Science Collection ProQuest Central Korea Biological Science Collection Industrial and Applied Microbiology Abstracts (Microbiology A) ProQuest Central (New) ProQuest Biological Science Collection ProQuest One Academic Eastern Edition Coronavirus Research Database Biological Science Database ProQuest SciTech Collection Biotechnology and BioEngineering Abstracts ProQuest One Academic UKI Edition Engineering Research Database ProQuest One Academic ProQuest One Academic (New) MEDLINE - Academic
DatabaseTitleList	PubMed Publicly Available Content Database CrossRef MEDLINE - Academic
Database_xml	– sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: PIMPY name: Publicly Available Content Database url: http://search.proquest.com/publiccontent sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Biology
EISSN	2076-0817
ExternalDocumentID	oai_doaj_org_article_6460a16300e34441a65c8e7b2e2e4b70 PMC9145208 35631032 10_3390_pathogens11050511
Genre	Journal Article
GeographicLocations	South Africa Montenegro Croatia
GeographicLocations_xml	– name: South Africa – name: Montenegro – name: Croatia
GroupedDBID	53G 5VS 8FE 8FH AADQD AAHBH AAYXX ADBBV AFFHD AFKRA AFZYC ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BBNVY BCNDV BENPR BHPHI CCPQU CITATION DIK GROUPED_DOAJ HCIFZ HYE IAO IHR ITC KQ8 LK8 M48 M7P MODMG M~E OK1 PGMZT PHGZM PHGZT PIMPY PQGLB PROAC RPM NPM 7T7 8FD ABUWG AZQEC C1K COVID DWQXO FR3 GNUQQ P64 PKEHL PQEST PQQKQ PQUKI PRINS 7X8 PUEGO 5PM
ID	FETCH-LOGICAL-c4081-fd090e7f4a2bd19159438b2881a6a0935e10bf15882d143626dd39d9c53753f43
IEDL.DBID	M7P
ISSN	2076-0817
IngestDate	Fri Oct 03 12:28:22 EDT 2025 Tue Nov 04 01:39:44 EST 2025 Fri Sep 05 11:48:23 EDT 2025 Fri Jul 25 09:33:53 EDT 2025 Thu Jan 02 22:54:28 EST 2025 Tue Nov 18 22:34:26 EST 2025 Sat Nov 29 07:15:41 EST 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	5
Keywords	Omicron variant SARS-CoV-2 surveillance whole-genome sequencing Croatia
Language	English
License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c4081-fd090e7f4a2bd19159438b2881a6a0935e10bf15882d143626dd39d9c53753f43
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23
ORCID	0000-0001-8304-5519 0000-0002-9078-1773 0000-0002-2518-522X 0000-0002-9285-9052 0000-0003-0434-7514 0000-0002-1877-5547
OpenAccessLink	https://www.proquest.com/docview/2670344892?pq-origsite=%requestingapplication%
PMID	35631032
PQID	2670344892
PQPubID	2032351
ParticipantIDs	doaj_primary_oai_doaj_org_article_6460a16300e34441a65c8e7b2e2e4b70 pubmedcentral_primary_oai_pubmedcentral_nih_gov_9145208 proquest_miscellaneous_2671279247 proquest_journals_2670344892 pubmed_primary_35631032 crossref_primary_10_3390_pathogens11050511 crossref_citationtrail_10_3390_pathogens11050511
PublicationCentury	2000
PublicationDate	20220426
PublicationDateYYYYMMDD	2022-04-26
PublicationDate_xml	– month: 4 year: 2022 text: 20220426 day: 26
PublicationDecade	2020
PublicationPlace	Switzerland
PublicationPlace_xml	– name: Switzerland – name: Basel
PublicationTitle	Pathogens (Basel)
PublicationTitleAlternate	Pathogens
PublicationYear	2022
Publisher	MDPI AG MDPI
Publisher_xml	– name: MDPI AG – name: MDPI
References	Hill (ref_19) 2021; 6 ref_14 ref_36 ref_35 ref_12 ref_34 ref_11 Shu (ref_24) 2017; 22 ref_33 ref_10 ref_32 ref_31 ref_30 ref_17 ref_39 Altarawneh (ref_8) 2022; 386 ref_16 Scher (ref_20) 2021; 7 ref_38 ref_15 ref_37 Rambaut (ref_18) 2020; 5 Brown (ref_40) 2021; 325 Katoh (ref_43) 2019; 20 Blairon (ref_13) 2021; 297 ref_25 Khare (ref_22) 2021; 3 Elbe (ref_23) 2017; 1 ref_21 ref_42 ref_41 ref_1 Kidd (ref_26) 2021; 223 ref_3 ref_2 ref_29 ref_28 Letunic (ref_44) 2021; 49 ref_27 ref_9 He (ref_4) 2021; 2 ref_5 ref_7 ref_6
References_xml	– ident: ref_7 – ident: ref_28 – ident: ref_10 doi: 10.1101/2022.01.28.22270044 – ident: ref_30 – volume: 1 start-page: 33 year: 2017 ident: ref_23 article-title: Data, Disease and Diplomacy: GISAID’s Innovative Contribution to Global Health publication-title: Glob. Chall. doi: 10.1002/gch2.1018 – volume: 49 start-page: W293 year: 2021 ident: ref_44 article-title: Interactive Tree Of Life (ITOL) v5: An Online Tool for Phylogenetic Tree Display and Annotation publication-title: Nucleic Acid Res. doi: 10.1093/nar/gkab301 – ident: ref_5 – ident: ref_32 – ident: ref_3 – ident: ref_34 – ident: ref_11 – ident: ref_42 doi: 10.17504/protocols.io.bbmuik6w – ident: ref_16 – ident: ref_39 – ident: ref_37 – ident: ref_14 – ident: ref_33 doi: 10.3390/v13122354 – ident: ref_1 – ident: ref_35 – ident: ref_21 – ident: ref_9 doi: 10.1101/2022.01.25.22269794 – ident: ref_6 – volume: 386 start-page: 1288 year: 2022 ident: ref_8 article-title: Protection against the Omicron Variant from Previous SARS-CoV-2 Infection publication-title: N. Engl. J. Med. doi: 10.1056/NEJMc2200133 – ident: ref_25 – ident: ref_31 – ident: ref_29 – ident: ref_27 – ident: ref_2 – ident: ref_12 – volume: 2 start-page: 838 year: 2021 ident: ref_4 article-title: SARS-CoV-2 Omicron Variant: Characteristics and Prevention publication-title: MedComm doi: 10.1002/mco2.110 – volume: 6 start-page: 121 year: 2021 ident: ref_19 article-title: Tracking the International Spread of SARS-CoV-2 Lineages B.1.1.7 and B.1.351/501Y-V2 with Grinch publication-title: Wellcome Open Res. – ident: ref_41 – ident: ref_15 – volume: 297 start-page: 114248 year: 2021 ident: ref_13 article-title: The Challenge of Screening SARS-CoV-2 Variants of Concern with RT-QPCR: One Variant Can Hide Another publication-title: J. Virol. Methods doi: 10.1016/j.jviromet.2021.114248 – ident: ref_38 – ident: ref_17 – volume: 7 start-page: veab064 year: 2021 ident: ref_20 article-title: Assignment of Epidemiological Lineages in an Emerging Pandemic Using the Pangolin Tool publication-title: Virus Evol. doi: 10.1093/ve/veab064 – ident: ref_36 – volume: 22 start-page: 30494 year: 2017 ident: ref_24 article-title: GISAID: Global Initiative on Sharing All Influenza Data—From Vision to Reality publication-title: Euro Surveill. doi: 10.2807/1560-7917.ES.2017.22.13.30494 – volume: 20 start-page: 1160 year: 2019 ident: ref_43 article-title: MAFFT Online Service: Multiple Sequence Alignment, Interactive Sequence Choice and Visualization publication-title: Brief Bioinform. doi: 10.1093/bib/bbx108 – volume: 223 start-page: 1666 year: 2021 ident: ref_26 article-title: S-Variant SARS-CoV-2 Lineage B1.1.7 Is Associated With Significantly Higher Viral Load in Samples Tested by TaqPath Polymerase Chain Reaction publication-title: J. Infect. Dis. doi: 10.1093/infdis/jiab082 – volume: 5 start-page: 1403 year: 2020 ident: ref_18 article-title: A Dynamic Nomenclature Proposal for SARS-CoV-2 Lineages to Assist Genomic Epidemiology publication-title: Nat. Microbiol. doi: 10.1038/s41564-020-0770-5 – volume: 3 start-page: 1049 year: 2021 ident: ref_22 article-title: GISAID’s Role in Pandemic Response publication-title: CCDCW – volume: 325 start-page: 2115 year: 2021 ident: ref_40 article-title: S-Gene Target Failure as a Marker of Variant B.1.1.7 Among SARS-CoV-2 Isolates in the Greater Toronto Area, December 2020 to March 2021 publication-title: JAMA doi: 10.1001/jama.2021.5607
SSID	ssj0000800817
Score	2.208779
Snippet	Background: Due to rapid spread, the Omicron variant has become the dominant SARS-CoV-2 variant responsible for infections worldwide. We present the first... Due to rapid spread, the Omicron variant has become the dominant SARS-CoV-2 variant responsible for infections worldwide. We present the first detection of the...
SourceID	doaj pubmedcentral proquest pubmed crossref
SourceType	Open Website Open Access Repository Aggregation Database Index Database Enrichment Source
StartPage	511
SubjectTerms	Communication Contact tracing Coronaviruses COVID-19 COVID-19 vaccines Croatia Depletion Disease transmission Epidemics Epidemiology Gene sequencing Influenza Laboratories Medical research mRNA Mutation Omicron variant Pandemics Patients Phylogenetics Phylogeny SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 surveillance Viral diseases Whole genome sequencing Workshops
SummonAdditionalLinks	– databaseName: Open Access: DOAJ - Directory of Open Access Journals dbid: DOA link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Nb9QwELWqikpcEB8FUkplJE5IFrHjxPaxXbriVFAXqt4iO7bVoNZZbbZIvfVH8Av5JYyddLVbEFy4xmPJHo8178mTNwi9NVw7X3igJRwoCiDwnBhHLTFal17wSnLqU7MJcXIiz8_V57VWX7EmbJAHHhz3vuJVrmkUhnIFh9ytq7KRThjmmONGJLYOqGeNTH0bcZCkYnjGLIDXx_rqiw7OpId8B1mf0o1ElPT6_wQy79dKriWf6WP0aESN-HBY7RO05cJTtDP0kbx5hvTs8HRGJt0ZYfjTVSyxC_gMSDB4DbcBTxYd-F__vP1xquetxR_cMhVgBdx5DAAQT1vAgHgCCQ3rYKN935OjpMqJZ3OAlXYXfZ0ef5l8JGPvBNJw2DnxNle5E55rZixwslLxQhomJThQx8dPR3PjaQkA2wJkAlpjbaGsasoCCIznxXO0HbrgXiLsTGWNpM6Cw7kXShplpOGmYY0oHVcZyu8cWTejsHjsb3FZA8GIvq9_832G3q2mzAdVjb8ZH8XTWRlGQez0AcKkHsOk_leYZGj_7mzr8Zb2NatEVDyUimXozWoY7ld8NNHBddfJhkaRRS4y9GIIhdVKirKKbdpgttgIko2lbo6E9iJpeCvKS4jbvf-xt1foIYs_ZeScsGofbS8X1-41etB8X7b94iBdjF_9QhJl priority: 102 providerName: Directory of Open Access Journals
Title	SARS-CoV-2 Omicron Variant in Croatia—Rapid Detection of the First Case and Cross-Border Spread
URI	https://www.ncbi.nlm.nih.gov/pubmed/35631032 https://www.proquest.com/docview/2670344892 https://www.proquest.com/docview/2671279247 https://pubmed.ncbi.nlm.nih.gov/PMC9145208 https://doaj.org/article/6460a16300e34441a65c8e7b2e2e4b70
Volume	11
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 2076-0817 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000800817 issn: 2076-0817 databaseCode: DOA dateStart: 20120101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 2076-0817 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000800817 issn: 2076-0817 databaseCode: M~E dateStart: 20120101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 2076-0817 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000800817 issn: 2076-0817 databaseCode: M7P dateStart: 20120301 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 2076-0817 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000800817 issn: 2076-0817 databaseCode: BENPR dateStart: 20120301 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 2076-0817 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000800817 issn: 2076-0817 databaseCode: PIMPY dateStart: 20120301 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Nj9MwELXYXZC48L1sYKmMxAkpInac2D6hbWkFB0rVwqqcIjt22EhsUpouEhfEj-AX8ksYO2mggPbCJYfYkSZ-duaNPXmD0BPNlC3iAsISBiEKMPAo1JaYUCuVFJylgpHCF5vg06lYLuWs23BrurTK7TfRf6hNnbs98mc05U6dTkj6fPUpdFWj3OlqV0JjDx04lYTYp-7N-j0Wx4YE4e1hZgzRvcuyPqsBmQa8Hvh-QnbckVft_xfV_DNj8jcXNLn5v8bfQjc68olP2tlyG12x1R10rS1H-eUuUouT-SIc1achxW_OXaZehU8hlobBx2WFR-saYFQ_vn2fq1Vp8Au78XlcFa4LDDwST0qgkngEfhGryrj-TRMOvbgnXqyAnZp76N1k_Hb0MuxKMIQ5g6ELCxPJyPKCKaoNhHaJZLHQVAiiUuXOUC2JdEES4OkGmBdER8bE0sg8iSEOKlh8iParurJHCFudGi2INdQyVnAptNRCM53TnCeWyQBFWySyvNMnd2UyPmYQpzjwsr_AC9DT_pFVK85xWeehg7fv6HS1_Y16_SHrlmmWsjRSxMmQWcCLwVsmubBcUwtWax4F6HgLcNYt9ib7hW6AHvfNsEzd2YuqbH3h-xCn1ch4gO63c6m3JE5SV-0NnuY7s2zH1N2WqjzzUuCSsIRG4sHlZj1E16n7ayNiIU2P0f5mfWEfoav5503ZrAdojy_FAB0Mx9PZfOA3JQZ-Hbnr1zG0zF69nr3_Cf5GKA0
linkProvider	ProQuest
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V3NbtQwEB6VLQgu_P8sFDASXJAiYseJnQNC7ZZVV22XVbdU7SnYsUMjQbJstqDeeAieg4fiSRgn2YUF1FsPXGM7cuLPM994xjMATzVXNgsyNEs4mijIwH1PW2o8rVSYCR5JTrO62IQYDuXhYTxage_zuzAurHIuE2tBbcrUnZG_YJFw2elkzF5NPnmuapTzrs5LaDSw2LanX9Bkq14ONnF9nzHWf73f2_LaqgJeylH_eZnxY9-KjCumDVorYcwDqZmUVEXKuQUt9XVGQ6SeBskEEn5jgtjEaRggtc94gO-9AKscwS47sDoa7I6OFqc6jn9JKhr3aRDEvovrPi4RCxXqWWQblC4pwLpOwL_I7Z8xmr8pvf61_-13XYerLb0m681-uAErtrgJl5qCm6e3QI3X98ZerzzwGHnz0cUiFuRA4R4sZiQvSG9aIlDVj6_f9tQkN2TTzupItYKUGUGmTPo5kmXSQ81PVGFc_6ryNur0pWQ8Qf5tbsPbc_m-O9ApysLeA2J1ZLSk1jDLeSZiqWMtNdcpS0VoedwFf77ySdpmYHeFQD4kaIk5sCR_gaULzxdDJk36kbM6bzg4LTq6zOH1g3L6PmkFURLxyFfUJVqziA-OXxmm0grNLM5aC78La3NAJa04q5JfaOrCk0UzCiLnXVKFLU_qPtRlo-SiC3cb7C5mEoSRq2eHo8USqpemutxS5Md1svOY8pD58v7Z03oMl7f2d3eSncFw-wFcYe6Ois89Fq1BZzY9sQ_hYvp5llfTR-2OJfDuvFH_ExmBfFA
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V3NbtQwELZKC4gL_z-BAkaCC1LU2HFi-4BQu8uKVWFZdaEqp2DHNl0JkmWzBfXGQ_A0PA5Pwjg_Cwuotx64xnY0Tj7PfGOPZxB6qJmyLnbgljBwUYCBR6G2xIRaqcRxlgpGXF1sgo9G4uBAjtfQ9-4ujA-r7HRirahNmfs98i2acp-dTki65dqwiHF_8HT2KfQVpPxJa1dOo4HIrj3-Au5b9WTYh3_9iNLBs9e952FbYSDMGdjC0JlIRpY7pqg24LkkksVCUyGISpU_IrQk0o4kQEMNEAsg_8bE0sg8iYHmOxbDe8-gDaDkDNbYxnj4cvx2ucPjuZggvDlKjWMZ-RjvwxJwUYHNBeZByIoxrGsG_Ivo_hmv-ZsBHFz6nz_dZXSxpd14u1knV9CaLa6ic00hzuNrSE229yZhr9wPKX710ccoFnhfwdosFnha4N68BACrH1-_7anZ1OC-XdQRbAUuHQYGjQdTING4B4wAq8L4_lUV7tRpTfFkBrzcXEdvTmV-N9B6URb2FsJWp0YLYg21jDkuhZZaaKZzmvPEMhmgqENBlreZ2X2BkA8ZeGgeONlfwAnQ4-WQWZOW5KTOOx5ay44-o3j9oJy_z1oFlaUsjRTxCdgsYIXBLJNcWK6pBak1jwK02YEra9Vclf1CVoAeLJtBQflTJ1XY8qjuQ3yWSsYDdLPB8VKSOEl9nTsYzVcQviLqaksxPayToEvCEhqJ2yeLdR-dB6hnL4aj3TvoAvVXVyIW0nQTrS_mR_YuOpt_Xkyr-b128WL07rRB_xOV54UQ
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=SARS-CoV-2+Omicron+Variant+in+Croatia-Rapid+Detection+of+the+First+Case+and+Cross-Border+Spread&rft.jtitle=Pathogens+%28Basel%29&rft.au=Feren%C4%8Dak%2C+Ivana&rft.au=Obrovac%2C+Mihaela&rft.au=%C5%BDmak%2C+Ljiljana&rft.au=Kuzle%2C+Josipa&rft.date=2022-04-26&rft.issn=2076-0817&rft.eissn=2076-0817&rft.volume=11&rft.issue=5&rft_id=info:doi/10.3390%2Fpathogens11050511&rft.externalDBID=NO_FULL_TEXT
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2076-0817&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2076-0817&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2076-0817&client=summon