Pulmonary nontuberculous mycobacterial infections and environmental factors: A review of the literature

Pulmonary nontuberculous mycobacterial (pNTM) infection is mainly acquired through the inhalation of bioaerosols. Nevertheless, behavioural restrictions are rarely given by clinicians to susceptible populations, in part because the available guidelines for pNTM management emphasize more diagnosis an...

Celý popis

Uložené v:
Podrobná bibliografia
Vydané v:Respiratory medicine Ročník 189; s. 106660
Hlavní autori: Gardini, Giulia, Ori, Margherita, Codecasa, Luigi Ruffo, Matteelli, Alberto
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: England 01.11.2021
Predmet:
Air Microbiology
Disease Susceptibility
Environmental Exposure
Humans
Lung Diseases - microbiology
Lung Diseases - prevention & control
Mycobacterium Infections, Nontuberculous - microbiology
Mycobacterium Infections, Nontuberculous - prevention & control
Risk Factors
Soil Microbiology
Prevention
Water
Soil
Environmental exposure
Review
Nontuberculous mycobacteria
ISSN:1532-3064, 1532-3064
On-line prístup:Zistit podrobnosti o prístupe
Tagy: Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
Abstract Pulmonary nontuberculous mycobacterial (pNTM) infection is mainly acquired through the inhalation of bioaerosols. Nevertheless, behavioural restrictions are rarely given by clinicians to susceptible populations, in part because the available guidelines for pNTM management emphasize more diagnosis and treatment than prevention. Aim of this review is to clarify if pNTM prevention should routinely include recommendations about risk reducing behaviors. We used PubMed as biomedical database. We limited our search to the publication period 2000 to 2020 with selected keyword combinations including "nontuberculous mycobacteria", "water", "soil", and "exposure". Titles and abstract of selected articles were systematically screened. Articles were included in the analysis if they were published under free access through the digital library of the University of Brescia (Italy), and provided full text either in English, French, German or Italian. Articles were excluded if the topic was beyond the aim of our study. Finally, we selected 20 articles. Studies disagree in identifying the type of aerosol posing the highest risk for the development of pNTM infection. In the retrieved publications the colonization of household niches has been associated with a higher risk of pNTM disease, such as in the exposure to shower aerosols. Considering the non-household settings, the exposure to aerosols in indoor swimming and the higher soil exposure (>2 h/week) seem to correlate with a higher risk to develop pNTM disease. According to our findings, randomized behavioural intervention studies are missing. Stringent scientific evidence is missing to formulate recommendations on behavioural risk reduction for pNTM.
AbstractList Pulmonary nontuberculous mycobacterial (pNTM) infection is mainly acquired through the inhalation of bioaerosols. Nevertheless, behavioural restrictions are rarely given by clinicians to susceptible populations, in part because the available guidelines for pNTM management emphasize more diagnosis and treatment than prevention. Aim of this review is to clarify if pNTM prevention should routinely include recommendations about risk reducing behaviors.BACKGROUNDPulmonary nontuberculous mycobacterial (pNTM) infection is mainly acquired through the inhalation of bioaerosols. Nevertheless, behavioural restrictions are rarely given by clinicians to susceptible populations, in part because the available guidelines for pNTM management emphasize more diagnosis and treatment than prevention. Aim of this review is to clarify if pNTM prevention should routinely include recommendations about risk reducing behaviors.We used PubMed as biomedical database. We limited our search to the publication period 2000 to 2020 with selected keyword combinations including "nontuberculous mycobacteria", "water", "soil", and "exposure". Titles and abstract of selected articles were systematically screened. Articles were included in the analysis if they were published under free access through the digital library of the University of Brescia (Italy), and provided full text either in English, French, German or Italian. Articles were excluded if the topic was beyond the aim of our study. Finally, we selected 20 articles.METHODSWe used PubMed as biomedical database. We limited our search to the publication period 2000 to 2020 with selected keyword combinations including "nontuberculous mycobacteria", "water", "soil", and "exposure". Titles and abstract of selected articles were systematically screened. Articles were included in the analysis if they were published under free access through the digital library of the University of Brescia (Italy), and provided full text either in English, French, German or Italian. Articles were excluded if the topic was beyond the aim of our study. Finally, we selected 20 articles.Studies disagree in identifying the type of aerosol posing the highest risk for the development of pNTM infection. In the retrieved publications the colonization of household niches has been associated with a higher risk of pNTM disease, such as in the exposure to shower aerosols. Considering the non-household settings, the exposure to aerosols in indoor swimming and the higher soil exposure (>2 h/week) seem to correlate with a higher risk to develop pNTM disease. According to our findings, randomized behavioural intervention studies are missing.RESULTSStudies disagree in identifying the type of aerosol posing the highest risk for the development of pNTM infection. In the retrieved publications the colonization of household niches has been associated with a higher risk of pNTM disease, such as in the exposure to shower aerosols. Considering the non-household settings, the exposure to aerosols in indoor swimming and the higher soil exposure (>2 h/week) seem to correlate with a higher risk to develop pNTM disease. According to our findings, randomized behavioural intervention studies are missing.Stringent scientific evidence is missing to formulate recommendations on behavioural risk reduction for pNTM.CONCLUSIONSStringent scientific evidence is missing to formulate recommendations on behavioural risk reduction for pNTM.
Pulmonary nontuberculous mycobacterial (pNTM) infection is mainly acquired through the inhalation of bioaerosols. Nevertheless, behavioural restrictions are rarely given by clinicians to susceptible populations, in part because the available guidelines for pNTM management emphasize more diagnosis and treatment than prevention. Aim of this review is to clarify if pNTM prevention should routinely include recommendations about risk reducing behaviors. We used PubMed as biomedical database. We limited our search to the publication period 2000 to 2020 with selected keyword combinations including "nontuberculous mycobacteria", "water", "soil", and "exposure". Titles and abstract of selected articles were systematically screened. Articles were included in the analysis if they were published under free access through the digital library of the University of Brescia (Italy), and provided full text either in English, French, German or Italian. Articles were excluded if the topic was beyond the aim of our study. Finally, we selected 20 articles. Studies disagree in identifying the type of aerosol posing the highest risk for the development of pNTM infection. In the retrieved publications the colonization of household niches has been associated with a higher risk of pNTM disease, such as in the exposure to shower aerosols. Considering the non-household settings, the exposure to aerosols in indoor swimming and the higher soil exposure (>2 h/week) seem to correlate with a higher risk to develop pNTM disease. According to our findings, randomized behavioural intervention studies are missing. Stringent scientific evidence is missing to formulate recommendations on behavioural risk reduction for pNTM.
Author Matteelli, Alberto
Ori, Margherita
Gardini, Giulia
Codecasa, Luigi Ruffo
Author_xml – sequence: 1
  givenname: Giulia
  surname: Gardini
  fullname: Gardini, Giulia
  email: giulia.gardini90@gmail.com
  organization: University of Brescia, Division of Tropical and Infectious Diseases, Spedali Civili Hospital, Brescia, Italy. Electronic address: giulia.gardini90@gmail.com
– sequence: 2
  givenname: Margherita
  surname: Ori
  fullname: Ori, Margherita
  email: margherita.ori@gmail.com
  organization: Division of Pneumology, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: margherita.ori@gmail.com
– sequence: 3
  givenname: Luigi Ruffo
  surname: Codecasa
  fullname: Codecasa, Luigi Ruffo
  email: luigiruffo.codecasa@ospedaleniguarda.it
  organization: Regional TB Reference Centre, Istituto Villa Marelli, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy. Electronic address: luigiruffo.codecasa@ospedaleniguarda.it
– sequence: 4
  givenname: Alberto
  surname: Matteelli
  fullname: Matteelli, Alberto
  email: alberto.matteelli@unibs.it
  organization: University of Brescia, Division of Tropical and Infectious Diseases, Spedali Civili Hospital, Brescia, Italy. Electronic address: alberto.matteelli@unibs.it
BackLink https://www.ncbi.nlm.nih.gov/pubmed/34715617$$D View this record in MEDLINE/PubMed
BookMark eNpNkE1LAzEQhoNU7If-AQ-So5etSTbJut5K8QsKetDzko-JpuwmNbtb6b83YAVPM8w888I8czQJMQBCl5QsKaHyZrtMHdglI4zmgZSSnKAZFSUrSiL55F8_RfO-3xJCas7JGZqWvKJC0mqGPl7HtotBpQPO6cOoIZmxjWOPu4OJWpkBklct9sGBGXwMPVbBYgh7n2LoIAx56TIWU3-HVzjB3sM3jg4Pn4Bbn8_VMCY4R6dOtT1cHOsCvT_cv62fis3L4_N6tSkMJ9VQuFtupCmdhdpqBqYiYDXYUhGiGHFWCUEqrisDWlnNWWml0MwxAZwa6wRboOvf3F2KXyP0Q9P53kDbqgD5q4aJmtCy4rXM6NURHXX22OyS77KH5k8O-wGV7m1J
CitedBy_id crossref_primary_10_1016_j_ccm_2023_06_011
crossref_primary_10_1016_j_heliyon_2024_e35311
crossref_primary_10_1371_journal_pntd_0013204
crossref_primary_10_1134_S0006297924603496
ContentType Journal Article
Copyright Copyright © 2021 Elsevier Ltd. All rights reserved.
Copyright_xml – notice: Copyright © 2021 Elsevier Ltd. All rights reserved.
CorporateAuthor IRENE Network
CorporateAuthor_xml – name: IRENE Network
DBID CGR
CUY
CVF
ECM
EIF
NPM
7X8
DOI 10.1016/j.rmed.2021.106660
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic
MEDLINE
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: 7X8
  name: MEDLINE - Academic
  url: https://search.proquest.com/medline
  sourceTypes: Aggregation Database
DeliveryMethod no_fulltext_linktorsrc
Discipline Medicine
EISSN 1532-3064
ExternalDocumentID 34715617
Genre Journal Article
Review
GroupedDBID ---
--K
--M
.1-
.55
.FO
.GJ
.~1
0R~
123
1B1
1P~
1RT
1~.
1~5
29P
3O-
4.4
457
4G.
53G
5RE
5VS
7-5
71M
8P~
9JM
AABNK
AAEDT
AAEDW
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AAQXK
AATTM
AAXKI
AAXUO
AAYWO
ABBQC
ABFNM
ABFRF
ABJNI
ABMAC
ABMZM
ABOCM
ABWVN
ABXDB
ACDAQ
ACGFO
ACGFS
ACIEU
ACPRK
ACRLP
ACRPL
ACVFH
ADBBV
ADCNI
ADEZE
ADFRT
ADMUD
ADNMO
ADVLN
AEBSH
AEFWE
AEIPS
AEKER
AENEX
AEUPX
AEVXI
AEXQZ
AFCTW
AFFNX
AFJKZ
AFPUW
AFRAH
AFRHN
AFTJW
AFXIZ
AGCQF
AGHFR
AGQPQ
AGRNS
AGUBO
AGYEJ
AHHHB
AHMBA
AIEXJ
AIGII
AIIUN
AIKHN
AITUG
AJRQY
AJUYK
AKBMS
AKRWK
AKYEP
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
ANKPU
ANZVX
APXCP
AQUVI
ASPBG
AVWKF
AXJTR
AZFZN
BKEYQ
BKOJK
BLXMC
BNPGV
BNQBC
BPHCQ
BVXVI
CAG
CGR
COF
CS3
CUY
CVF
DU5
EBS
ECM
EFJIC
EFKBS
EIF
EJD
EMOBN
EO8
EO9
EP2
EP3
EX3
F5P
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
GBLVA
HEJ
HMK
HMO
HVGLF
HZ~
IHE
IXB
J1W
K-O
KOM
L7B
M29
M41
MO0
N9A
NPM
O-L
O9-
OAUVE
OI-
OK1
OU.
OZT
P-8
P-9
P2P
PC.
PQQKQ
PROAC
Q38
R2-
RIG
ROL
RPZ
RSU
SAE
SDF
SDG
SEL
SES
SEW
SPCBC
SSH
SSZ
SV3
T5K
UHS
UV1
WH7
WOW
WUQ
X7M
Z5R
ZGI
ZXP
~G-
7X8
ACLOT
EFLBG
~HD
ID FETCH-LOGICAL-c407t-f84c6c3fde9db2ec70edbed3a00a20fda55074b7cebadb423d65b2f25e41cdf52
IEDL.DBID 7X8
ISICitedReferencesCount 4
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000740941800011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 1532-3064
IngestDate Sun Sep 28 08:58:15 EDT 2025
Mon Jul 21 05:25:47 EDT 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Keywords Prevention
Water
Soil
Environmental exposure
Review
Nontuberculous mycobacteria
Language English
License Copyright © 2021 Elsevier Ltd. All rights reserved.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c407t-f84c6c3fde9db2ec70edbed3a00a20fda55074b7cebadb423d65b2f25e41cdf52
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
OpenAccessLink https://www.clinicalkey.com/#!/content/1-s2.0-S0954611121003681
PMID 34715617
PQID 2590137496
PQPubID 23479
ParticipantIDs proquest_miscellaneous_2590137496
pubmed_primary_34715617
PublicationCentury 2000
PublicationDate 2021 Nov-Dec
20211101
PublicationDateYYYYMMDD 2021-11-01
PublicationDate_xml – month: 11
  year: 2021
  text: 2021 Nov-Dec
PublicationDecade 2020
PublicationPlace England
PublicationPlace_xml – name: England
PublicationTitle Respiratory medicine
PublicationTitleAlternate Respir Med
PublicationYear 2021
SSID ssj0009440
Score 2.3647738
SecondaryResourceType review_article
Snippet Pulmonary nontuberculous mycobacterial (pNTM) infection is mainly acquired through the inhalation of bioaerosols. Nevertheless, behavioural restrictions are...
SourceID proquest
pubmed
SourceType Aggregation Database
Index Database
StartPage 106660
SubjectTerms Air Microbiology
Disease Susceptibility
Environmental Exposure
Humans
Lung Diseases - microbiology
Lung Diseases - prevention & control
Mycobacterium Infections, Nontuberculous - microbiology
Mycobacterium Infections, Nontuberculous - prevention & control
Risk Factors
Soil Microbiology
Title Pulmonary nontuberculous mycobacterial infections and environmental factors: A review of the literature
URI https://www.ncbi.nlm.nih.gov/pubmed/34715617
https://www.proquest.com/docview/2590137496
Volume 189
WOSCitedRecordID wos000740941800011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText
inHoldings 1
isFullTextHit
isPrint
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV05T8MwFLaAIsTCfZRLRmK1SJzDMQuqEBVLqw4gdYt8IqSSlqRB6r_nOXEpAwMSS4Zc8vH8_H1-F0I3AOtjHfGEZKlhJDYiIZICcbWhDbjJUkVD1RSbYMNhNh7zkT9wq7xb5VInNopaT5U7I7-lLkgyYjFP72cfxFWNctZVX0JjHXUigDJOqtl4lS2cx21AZBJR4pC2D5pp_btK2G2AH9IQbqTLFJW_Qsxmq-nv_reRe2jHg0zca6ViH62Z4gBtDbwZ_RC9juoJvCrKBQb2P6-lKVU9mdYVfl8oWOBNAmf4wdJTq6iwKDT-ERQHD32lnjvcw238C55aDHAST74zNR-hl_7j88MT8RUXiAJiNyc2i1WqIqsN15IaxQKjpdGRCAJBA6uFy34WS6aMFFoCEtNpIqmliYlDpW1Cj9EGtNucIswpy6wNBc8okDCZcq51AuTIcR5QErqLrpdDmINEOzOFKAz0NF8NYhedtPOQz9rUG3kEeykgPnb2h6_P0bab3jZw8AJ1LKxnc4k21ef8rSqvGlGB63A0-AIJ4MtH
linkProvider ProQuest
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Pulmonary+nontuberculous+mycobacterial+infections+and+environmental+factors%3A+A+review+of+the+literature&rft.jtitle=Respiratory+medicine&rft.au=Gardini%2C+Giulia&rft.au=Ori%2C+Margherita&rft.au=Codecasa%2C+Luigi+Ruffo&rft.au=Matteelli%2C+Alberto&rft.date=2021-11-01&rft.issn=1532-3064&rft.eissn=1532-3064&rft.volume=189&rft.spage=106660&rft_id=info:doi/10.1016%2Fj.rmed.2021.106660&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1532-3064&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1532-3064&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1532-3064&client=summon