Impact of Deep Learning-based Optimization Algorithm on Image Quality of Low-dose Coronary CT Angiography with Noise Reduction: A Prospective Study

To evaluate deep learning (DL)-based optimization algorithm for low-dose coronary CT angiography (CCTA) image noise reduction and image quality (IQ) improvement. A postprocessing platform for the CCTA image was built using a DL-based algorithm. Seventy subjects referred for CCTA were randomly divide...

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Vydané v:Academic radiology Ročník 27; číslo 9; s. 1241
Hlavní autori: Liu, Peijun, Wang, Man, Wang, Yining, Yu, Min, Wang, Yun, Liu, Zhuoheng, Li, Yumei, Jin, Zhengyu
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 01.09.2020
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ISSN:1878-4046, 1878-4046
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Shrnutí:To evaluate deep learning (DL)-based optimization algorithm for low-dose coronary CT angiography (CCTA) image noise reduction and image quality (IQ) improvement. A postprocessing platform for the CCTA image was built using a DL-based algorithm. Seventy subjects referred for CCTA were randomly divided into two groups (study group A with 80 kVp and control group B with 100 kVp). Group C was obtained by DL optimization of group A. Subjective IQ was blindly graded by two experienced radiologists on a four-point scale (4-excellent,1-poor). The image noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were calculated to evaluate IQ objectively. The difference between the time consumed of iterative reconstruction and DL algorithm was also recorded. The subjective IQ score of group C using the DL algorithm was significantly better than that of group A (p = 0.005). The noise of group C was significantly decreased, while SNR and CNR were significantly increased compared to group A (p < 0.001). The subjective IQ scores were lower in group A compared to group B (p = 0.037), whereas subjective IQ scores in group C were not significantly different (p = 0.874). For objective IQ, the noise of group A was significantly higher, while SNR and CNR were significantly lower than that of group B (p < 0.05). There was no significant difference in noise and SNR between group C and group B (p > 0.05), but CNR in group C was significantly higher than that in group B (p < 0.05). The DL algorithm processes the image twice as fast as the iterative reconstruction speed. The DL-based optimization algorithm could effectively improve the IQ of low-dose CCTA by noise reduction.
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ISSN:1878-4046
1878-4046
DOI:10.1016/j.acra.2019.11.010