Assessing the unified airway hypothesis in children via transcriptional profiling of the airway epithelium

Emerging evidence suggests that disease vulnerability is expressed throughout the airways, the so-called unified airway hypothesis, but the evidence to support this is predominantly indirect. We sought to establish the transcriptomic profiles of the upper and lower airways and determine their level...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Journal of allergy and clinical immunology Ročník 145; číslo 6; s. 1562 - 1573
Hlavní autori:	Kicic, Anthony, de Jong, Emma, Ling, Kak-Ming, Nichol, Kristy, Anderson, Denise, Wark, Peter A.B., Knight, Darryl A., Bosco, Anthony, Stick, Stephen M., Kicic-Starcevich, Elizabeth, Garratt, Luke W., Padros-Goosen, Marc, Tan, Ee-Lyn, Sutanto, Erika N., Looi, Kevin, Hillas, Jessica, Iosifidis, Thomas, Shaw, Nicole C., Montgomery, Samuel T., Martinovich, Kelly M., Lannigan, Francis J., Bergesio, Ricardo, Lee, Bernard, Vijaya-Sekeran, Shyan, Swan, Paul, Heaney, Mairead, Forsyth, Ian, Schoep, Tobias, Larcombe, Alexander, Hunter, Monica, McGee, Kate, Millington, Nyssa, Poh, Matthew W.-P., Laucirica, Daniel R., Schofield, Craig, McLean, Samantha, Landwehr, Katherine, Farrow, Nigel, Roscioli, Eugene, Parsons, David, Grainge, Christopher, Reid, Andrew T., Loo, Su-Ling, Veerati, Punnam C.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Elsevier Inc 01.06.2020
Predmet:	Adolescent Airway epithelium biological processes Cell Adhesion Molecules - genetics Chemokine CCL26 - genetics Child Child, Preschool Cyclooxygenase 1 - genetics Epithelial Cells - metabolism Female gene expression Humans Hypersensitivity - genetics Male Receptors, Interleukin-1 Type I - genetics Respiratory Mucosa - metabolism Respiratory Sounds - genetics Respiratory System - metabolism Transcriptome - genetics transcriptomics unified airway hypothesis NTRK1 POSTN CDH Airway epithelium KRT CCL CST4 CST2 IL1RL1 CST1 transcriptomics CLCA1 unified airway hypothesis biological processes gene expression
ISSN:	0091-6749, 1097-6825, 1097-6825
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!