Effects of MRI image normalization techniques in prostate cancer radiomics

•Normalizing images with respect to healthy prostate tissue is optimal.•Histogram-based normalization should be used otherwise.•Over 87% of radiomic features drastically change after normalization.•Improper normalization is worse than no normalization. The variance in intensities of MRI scans is a f...

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Bibliographic Details
Published in:	Physica medica Vol. 71; pp. 7 - 13
Main Authors:	Isaksson, Lars J., Raimondi, Sara, Botta, Francesca, Pepa, Matteo, Gugliandolo, Simone G., De Angelis, Simone P., Marvaso, Giulia, Petralia, Giuseppe, De Cobelli, Ottavio, Gandini, Sara, Cremonesi, Marta, Cattani, Federica, Summers, Paul, Jereczek-Fossa, Barbara A.
Format:	Journal Article
Language:	English
Published:	Italy Elsevier Ltd 01.03.2020
Subjects:	Algorithms Humans Image normalization Image Processing, Computer-Assisted - methods Machine Learning Magnetic Resonance Imaging Male MRI Prospective Studies Prostate - diagnostic imaging Prostate cancer Prostate-Specific Antigen - analysis Prostatic Neoplasms - diagnostic imaging Prostatic Neoplasms - radiotherapy Radiometry - methods Radiomics Image normalization MRI Prostate cancer Radiomics
ISSN:	1120-1797, 1724-191X, 1724-191X
Online Access:	Get full text
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