An evaluation of numerical integration algorithms for the estimation of the area under the curve (AUC) in pharmacokinetic studies

Six numerical integration algorithms based on linear and log trapezoidal methods as well as four cubic-spline methods were proposed for estimation of area under the curve (AUC). These six different algorithms were implemented using IMSL/IDL command language and evaluated using data simulated under f...

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Veröffentlicht in:	Biopharmaceutics & drug disposition Jg. 16; H. 1; S. 37
Hauptverfasser:	Yu, Z, Tse, F L
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.01.1995
Schlagworte:	Algorithms Biological Availability Models, Theoretical Pharmacokinetics Quality Control
ISSN:	0142-2782
Online-Zugang:	Weitere Angaben
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